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Proteasome Function Inhibition

Known as: Proteasome Inhibition 
Proteasome Inhibition involves interference with, or restraint of, the activities of macromolecular multicatalytic cellular structures in the cytosol… 
National Institutes of Health

Papers overview

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2009
2009
The proteasome inhibitor bortezomib has a striking clinical benefit in patients with multiple myeloma. It is unknown whether the… 
2006
2006
Liver, a central organ responsible for the metabolism of carbohydrates, proteins, and lipoproteins, is exposed to various kinds… 
Highly Cited
2004
Highly Cited
2004
The Epstein-Barr virus thwarts immune surveillance through a Gly-Ala repeat (GAr) within the viral Epstein-Barr virus-encoded… 
2004
2004
Anemia in cancer patients is associated with reduced quality of life and local failure after radiation treatment. However, the… 
Review
2004
Review
2004
Proteasomes are the main non-lysosomal, multicatalytic proteinase complexes involved in the degradation of most intracellular… 
Highly Cited
2002
Highly Cited
2002
The glucocorticoid receptor (GR) is a transcription factor, subject to several types of posttranslational modifications including… 
Highly Cited
2001
Highly Cited
1999
Highly Cited
1999
The proteasome, a multicatalytic protease, is known to degrade unfolded polypeptides with low specificity in substrate selection… 
Highly Cited
1997
Highly Cited
1997
We have studied specific effects of proteasome inhibition on cell cycle progression. To this end, the protease inhibitors MG115…