Proopiomelanocortin Deficiency

Despite being in the age of information technology, with a wealth of molecular data at our fingertips, relatively simple clinical… (More)

Patients with rare defects in the gene encoding proopiomelanocortin (POMC) have extreme early-onset obesity, hyperphagia… (More)

INTRODUCTION Common obesity is a multi-factorial trait, contributed by the "obesogenic" environment of caloric abundance and… (More)

The mature adrenal cortex is dependent upon proopiomelanocortin (POMC)-derived peptides for the maintenance of its size… (More)

The symptoms of severe early-onset obesity, adrenal insufficiency, and red hair define the proopiomelanocortin (POMC) deficiency… (More)