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Despite being in the age of information technology, with a wealth of molecular data at our fingertips, relatively simple clinical… (More)
- The New England journal of medicine
Patients with rare defects in the gene encoding proopiomelanocortin (POMC) have extreme early-onset obesity, hyperphagia… (More)
- Annals of the Academy of Medicine, Singapore
Common obesity is a multi-factorial trait, contributed by the "obesogenic" environment of caloric abundance and… (More)
The mature adrenal cortex is dependent upon proopiomelanocortin (POMC)-derived peptides for the maintenance of its size… (More)
The symptoms of severe early-onset obesity, adrenal insufficiency, and red hair define the proopiomelanocortin (POMC) deficiency… (More)