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Proopiomelanocortin Deficiency

Known as: OBESITY, EARLY-ONSET, ADRENAL INSUFFICIENCY, AND RED HAIR 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Adrenal gland hypofunctionObesityPro-Opiomelanocortin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Predicting Polygenic Obesity Using Genetic Information.
Except in rare cases, obesity tends to be a consequence of both an unhealthy lifestyle and a genetic susceptibility to gain… 
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Review
2017
Review
2017
Precision Metabolism: Hitting the Mark.
Despite being in the age of information technology, with a wealth of molecular data at our fingertips, relatively simple clinical… 
Highly Cited
2016
Highly Cited
2016
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
Patients with rare defects in the gene encoding proopiomelanocortin (POMC) have extreme early-onset obesity, hyperphagia… 
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Review
2009
Review
2009
The role of leptin-melanocortin system and human weight regulation: lessons from experiments of nature.
  • Y. Lee
  • Annals of the Academy of Medicine, Singapore
  • 2009
  • Corpus ID: 21049001
INTRODUCTION Common obesity is a multi-factorial trait, contributed by the "obesogenic" environment of caloric abundance and… 
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Highly Cited
2004
Highly Cited
2004
The effects of proopiomelanocortin deficiency on murine adrenal development and responsiveness to adrenocorticotropin.
The mature adrenal cortex is dependent upon proopiomelanocortin (POMC)-derived peptides for the maintenance of its size… 
Highly Cited
2003
Highly Cited
2003
Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.
The symptoms of severe early-onset obesity, adrenal insufficiency, and red hair define the proopiomelanocortin (POMC) deficiency… 
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