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Prominin-1, human

Known as: Prominin-like protein 1, Prominin-1, CD133 Antigen 
Prominin-1 (865 aa, ~97 kDa) is encoded by the human PROM1 gene. This protein may play a role in hematopoiesis, but an exact function has yet to be… 
National Institutes of Health

Related topics

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8 relations

Broader (1)

AC133 antigen
Eye DevelopmentGenes, RegulatorIntegral Membrane ProteinsPROM1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Expression of Cancer Stem Cell Markers OCT4 and CD133 in Transitional Cell Carcinomas
Background: Treatment failure, recurrence, and metastasis in bladder cancer are attributed to a subset of tumor cells expressing… 
2015
2015
Mir-152 inhibits cell proliferation and colony formation of CD133+ liver cancer stem cells by targeting KIT
AbstractmiR152 is involved in diverse biological functions and development of disease. This study investigates the role of mir… 
2013
2013
Curcumin enhances the effectiveness of cisplatin by suppressing CD133+ cancer stem cells in laryngeal carcinoma treatment
Chemoresistance is one of the major barriers to chemotherapeutic treatment and it has been established that CD133+ cancer stem… 
2011
2011
SDF-1α secreted by human CD133-derived multipotent stromal cells promotes neural progenitor cell survival through CXCR7.
We recently reported that concentrated conditioned medium (CdM) from human CD133-derived bone marrow progenitor cells (CD133 CdM… 
2010
2010
Immunohistochemical features of CD133 expression: association with resistance to chemoradiotherapy in rectal cancer.
CD133 has been described as a marker for cancer stem cells (CSCs) in colorectal cancer. Additionally, it has been reported that… 
2010
2010
Expression of CD133 correlates with differentiation of human colon cancer cells.
CD133 has been identified as a cancer stem cell marker in colon and several other cancers, but its function is still unknown. We… 
2009
2009
Elevated CD133, but not VEGF or EGFR, as a predictive marker of distant recurrence after preoperative chemoradiotherapy in rectal cancer.
CD133 has been postulated to be a colon cancer stem cell (CSCs) marker. Recent investigations suggest that CSCs might contribute… 
Highly Cited
2008
Highly Cited
2008
PPARγ agonists inhibit growth and expansion of CD133+ brain tumour stem cells
Brain tumour stem cells (BTSCs) are a small population of cells that has self-renewal, transplantation, multidrug resistance and… 
2008
2008
Cord blood-derived neurons are originated from CD133+/CD34 stem/progenitor cells in a cell-to-cell contact dependent manner.
Previous studies described that neurons could be generated in vitro from human umbilical cord blood cells. However, there are few… 
Highly Cited
2007
Highly Cited
2007
In vivo visualization of 111In labeled CD133+ peripheral blood stem cells after intracoronary administration in patients with chronic ischemic heart disease.
AIM Stem cell homing to injured tissue is necessary for local tissue repair. But homing of stem cells in chronic ischemic heart… 
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