Proline racemase
National Institutes of Health
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The enzyme proline racemase from the eukaryotic parasite Trypanosoma cruzi (responsible for endemic Chagas disease) catalyzes the…
Sir: During the course of screening for antiviral antibiotics from microorganisms isolated from soil samples we found that…
A rare population of bone marrow-derived ‘facilitating cells’ promote hematopoietic stem cell engraftment without causing graft…
The interconversion of L- and D-proline catalyzed by proline racemase has been studied. The entire time course of the approach to…
The isotope effects for the interconversion of L-proline and D-proline, catalyzed by proline racemase, have been determined in…
To test whether a reaction involving the making and/or breaking of two bonds at two sites is concerted (and proceeds through a…
Proline racemase exists in two states, one of which binds and isomerizes L-proline and the other of which binds and isomerizes D…
To probe the nature of the interconversion of the two unliganded forms of proline racemase, a number of experiments have been…