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Procarbazine

Known as: p-(N'-methylhydrazinomethyl)-N-isopropylbenzamide, 4-((2-Methylhydrazino)methyl)-N-isopropylbenzamide, p-(2-Methylhydrazinomethyl)-N-isopropylbenzamide 
A methylhydrazine derivative with antineoplastic and mutagenic activities. Although the exact mode of cytotoxicity has not been elucidated… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
BACKGROUND Grade 2 gliomas occur most commonly in young adults and cause progressive neurologic deterioration and premature death… Expand
Highly Cited
2013
Highly Cited
2013
PURPOSE Anaplastic oligodendroglioma are chemotherapy-sensitive tumors. We now present the long-term follow-up findings of a… Expand
Highly Cited
2010
Highly Cited
2010
In recent years, zwitterionic materials such as poly(carboxybetaine) (pCB) and poly(sulfobetaine) (pSB) have been applied to a… Expand
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Highly Cited
2009
Highly Cited
2009
PURPOSE The standard of care for anaplastic gliomas is surgery followed by radiotherapy. The NOA-04 phase III trial compared… Expand
Review
2008
Review
2008
DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. The… Expand
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Highly Cited
2006
Highly Cited
2006
PURPOSE Anaplastic oligodendrogliomas are more responsive to chemotherapy than high-grade astrocytomas. We investigated, in a… Expand
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Highly Cited
2002
Highly Cited
2002
PURPOSE To evaluate whether two commonly used newer platinum-based regimens offer any advantage over vinorelbine-cisplatin… Expand
Highly Cited
2000
Highly Cited
2000
Perhaps I am too concrete, too American in my way of thinking, but I need a level of accessibility that Claudio Neri 's book… Expand
Highly Cited
2000
Highly Cited
2000
A randomized, multicentre, open-label, phase II study compared temozolomide (TMZ), an oral second-generation alkylating agent… Expand
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Review
1989
Review
1989
Polychlorinated biphenyls (PCBs) as environmental contaminants often cannot be adequately described by reference to Aroclors or… Expand
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