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Probable ATP-Dependent RNA Helicase DDX5

Known as: DDX5, DEAD Box Protein 5, EC 3.6.4.13 
Probable ATP-dependent RNA helicase DDX5 (614 aa, ~69 kDa) is encoded by the human DDX5 gene. This protein is involved in both ATP hydrolysis and RNA… 
National Institutes of Health

Related topics

Related topics

15 relations
ATP HydrolysisAdenosine TriphosphatasesDDX5 geneDEAD Box Helicase p68

Broader (1)

RNA Helicase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
miRomics and Proteomics Reveal a miR-296-3p/PRKCA/FAK/Ras/c-Myc Feedback Loop Modulated by HDGF/DDX5/β-catenin Complex in Lung Adenocarcinoma
Purpose: This study was performed to identify the detailed mechanisms by which miR-296-3p functions as a tumor suppressor to… 
Highly Cited
2016
Highly Cited
2016
Regulation of the tumour suppressor PDCD4 by miR-499 and miR-21 in oropharyngeal cancers
The rates of oropharyngeal cancers such as tonsil cancers are increasing. The tumour suppressor protein Programmed Cell Death… 
Highly Cited
2015
Highly Cited
2015
Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing
Significance Alternative splicing of RNA allows a limited number of coding regions in the human genome to produce proteins with… 
Highly Cited
2013
Highly Cited
2013
DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia
Notch signaling is a highly conserved cell–cell communication pathway regulating normal development and tissue homeostasis… 
Highly Cited
2012
Highly Cited
2012
Feedback Regulation of Transcriptional Termination by the Mammalian Circadian Clock PERIOD Complex
The Inner Workings of a Clock Eukaryotic circadian clocks are built at least in part on transcriptional feedback loops, but the… 
Highly Cited
2011
Highly Cited
2011
RNA Helicase DDX5 Regulates MicroRNA Expression and Contributes to Cytoskeletal Reorganization in Basal Breast Cancer Cells*
RNA helicase DDX5 (also p68) is involved in all aspects of RNA metabolism and serves as a transcriptional coregulator, but its… 
Highly Cited
2010
Highly Cited
2010
Pleiotropic Effects of p300-mediated Acetylation on p68 and p72 RNA Helicase*
Here, we demonstrate that p68 (DDX5) and p72 (DDX17), two homologous RNA helicases and transcriptional cofactors, are substrates… 
Highly Cited
2009
Highly Cited
2009
SAGE analysis highlights the importance of p53csv, ddx5, mapkapk2 and ranbp2 to multiple myeloma tumorigenesis.
Highly Cited
2007
Highly Cited
2007
Redundant role of DEAD box proteins p68 (Ddx5) and p72/p82 (Ddx17) in ribosome biogenesis and cell proliferation
The DEAD box proteins encoded by the genes ddx5 (p68) and ddx17 (isoforms p72 and p82) are more closely related to each other… 
Highly Cited
2007
Highly Cited
2007
SUMO modification of the DEAD box protein p68 modulates its transcriptional activity and promotes its interaction with HDAC1
The nuclear protein p68 (also known as Ddx5) is a prototypic member of the ‘DEAD box’ family of RNA helicases, which has been… 
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