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Primary amyloidosis

Known as: AMYLOIDOSIS, SYSTEMIC, AMYLOIDOSIS, IDIOPATHIC, amyloidosis primary 
A plasma cell neoplasm that secretes an abnormal immunoglobulin, which deposits in tissues and forms a beta-pleated sheet structure that binds Congo… 
National Institutes of Health

Related topics

Related topics

23 relations

Broader (2)

AmyloidosisImmunoglobulin deposition disease
Atypical lymphocyteB lymphoblastB-LymphocytesCongestive heart failure

Narrower (1)

Primary Systemic Amyloidosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Potent in vitro and in vivo activity of sorafenib in multiple myeloma: induction of cell death, CD138‐downregulation and inhibition of migration through actin depolymerization
Despite considerable advances, multiple myeloma (MM) remains incurable and the development of novel therapies targeting the… 
Review
2008
Review
2008
The pathologist's perspective on vitreous opacities
BackgroundVitreous opacities are diverse in nature. Many underlying diseases are sight-threatening and several are also lethal… 
2004
2004
Two familial cases with tumor necrosis factor receptor-associated periodic syndrome caused by a non-cysteine mutation (T50M) in the TNFRSF1A gene associated with severe multiorganic amyloidosis.
An adolescent boy had had recurrent episodes of fever, abdominal pain, and arthralgias since the age of 7 years. Progressive… 
Highly Cited
2001
Highly Cited
2001
Brain Aβ amyloidosis in APPsw mice induces accumulation of presenilin‐1 and tau
APPsw transgenic mice (Tg2576) overproducing mutant amyloid β protein precursor (βAPP) show substantial brain Aβ amyloidosis and… 
1998
1998
A simple screening test for variant transthyretins associated with familial transthyretin amyloidosis using isoelectric focusing.
Review
1994
Review
1994
Role of bioincompatibility in dialysis morbidity and mortality.
1988
1988
Immunoglobulin synthesis in primary and myeloma amyloidosis.
Bone marrow cells from 14 patients with primary amyloidosis and two patients with myeloma amyloidosis were studied by… 
Highly Cited
1972
Highly Cited
1972
Immunoglobulins and amyloidosis. An immunologic study of sixty-two patients with biopsy-proved disease.
Review
1961
Review
1961
Joint Symptoms in Myelomatosis and Similar Conditions *
The commonest presenting symptom in myelo- matosis is pain in the back, which is frequently associated with vertebral collapse… 
Highly Cited
1953
Highly Cited
1953
Familial Primary Amyloidosis with Nervous System Involvement
PRIMARY AMYLOIDOSIS is a rare systemic disease; a total of about 80 cases have been reported in the 1iterature.l In the majority… 
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