Prenylamine

Known as: Prenylamine [Chemical/Ingredient], Prenilamina, N-(3,3-Diphenylpropyl)-alpha-methylphenethylamine 
A drug formerly used in the treatment of angina pectoris but superseded by less hazardous drugs. Prenylamine depletes myocardial catecholamine stores… (More)
National Institutes of Health

Related topics

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17 relations

Broader (4)

Adrenergic AgentsCalcium Channel BlockersSympathomimeticsVasodilator Agents

Narrower (6)

CorontinDifrilSegontindroprenylamine
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In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Papers overview

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1993
1993
Release of intracellular calcium by prenylamine in human ovarian tumour cells.
The effects of the calcium antagonist prenylamine on intracellular calcium concentration were studied in a human ovarian… (More)
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Review
1988
Review
1988
Basic mechanisms underlying prenylamine-induced 'torsade de pointes': differences between prenylamine and fendiline due to basic actions of the isomers.
The calcium antagonists prenylamine and fendiline both bind with rather low affinity to the dihydropyridine (nifedipine) binding… (More)
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1987
1987
Prevention of adriamycin-induced cardiotoxicity by prenylamine: a pilot double blind study.
Adriamycin (ADM) is an effective antineoplastic drug. However, the amount of ADM that can be administered must be limited because… (More)
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Highly Cited
1987
Highly Cited
1987
Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for calcium channel blockers.
A radioactive photoactive dihydropyridine calcium channel blocker, [3H]azidopine, was used to photoaffinity label plasma… (More)
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1986
1986
Amelioration of adriamycin-induced cardiotoxicity in rabbits by prenylamine and vitamins A and E.
The cardioprotective potentials of prenylamine (a calcium antagonist) and of a combination of vitamins A and E (a singlet oxygen… (More)
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1977
1977
Metabolism of DL-[14C]prenylamine in man.
Following oral administration of DL-[14C]prenylamine, about 40% of the dose administered was excreted in urine within 10 days… (More)
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1974
1974
Prenylamine in treatment of angina.
Forty-one patients with angina completed a double-blind cross-over trial in which the antianginal effects of prenylamine were… (More)
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1968
1968
On the metabolism of prenylamine (segontin®)
Nach oraler Verabfolgung von14C-Prenylamin (Segontin®) an Ratten werden nur Spuren des unveränderten Pharmakons im Harn… (More)
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1968
1968
The inhibition of the sarcoplasmic calcium pump by prenylamine, reserpine, chlorpromazine and imipramine
1. Reserpin, Prenylamin, Chlorpromazin und Imipramin hemmen sowohl die Geschwindigkeit der Calcium-Aufnahme als auch die der… (More)
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1963
1963
Prenylamine in angina pectoris.
The therapeutic value of prenylamine in angina pectoris was tested in two ways. Fourteen patients received 270 mg. of prenylamine… (More)
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