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Prenylamine

Known as: Prenylamine [Chemical/Ingredient], Prenilamina, N-(3,3-Diphenylpropyl)-alpha-methylphenethylamine 
A drug formerly used in the treatment of angina pectoris but superseded by less hazardous drugs. Prenylamine depletes myocardial catecholamine stores… Expand
National Institutes of Health

Related topics

Related topics

17 relations

Broader (4)

Adrenergic AgentsCalcium Channel BlockersSympathomimeticsVasodilator Agents

Narrower (6)

CorontinDifrilSegontindroprenylamine
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In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1989
Highly Cited
1989
The pharmacological properties of the peptide, endothelin
1 The effect of endothelin (ET‐1) has been studied on isolated vascular and non‐vascular preparations, using both functional and… Expand
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Highly Cited
1988
Highly Cited
1988
Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil.
  • A. Safa
  • Proceedings of the National Academy of Sciences…
  • 1988
    • Corpus ID: 46234938
Verapamil, a phenylalkylamine calcium channel blocker, has been shown to reverse multidrug resistance in tumor cells, possibly by… Expand
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Highly Cited
1988
Highly Cited
1988
Neuroregulatory and neuropathological actions of the ether-phospholipid platelet-activating factor.
Platelet-activating factor (PAF) is a naturally occurring phospholipid that serves as a critical mediator in diverse biological… Expand
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Highly Cited
1987
Highly Cited
1987
Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for calcium channel blockers.
A radioactive photoactive dihydropyridine calcium channel blocker, [3H]azidopine, was used to photoaffinity label plasma… Expand
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Highly Cited
1986
Highly Cited
1986
Amelioration of adriamycin-induced cardiotoxicity in rabbits by prenylamine and vitamins A and E.
The cardioprotective potentials of prenylamine (a calcium antagonist) and of a combination of vitamins A and E (a singlet oxygen… Expand
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Review
1983
Review
1983
History of Calcium Antagonists
The discovery of Ca++ antagonism as a new principle of action of coronary drugs reaches back to 1964, when we reported that two… Expand
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Highly Cited
1983
Highly Cited
1983
A unitary mechanism of calcium antagonist drug action.
[3H]Nitrendipine binding to drug receptor sites associated with calcium channels is allosterically regulated by a diverse group… Expand
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1977
1977
Ventricular arrhythmias caused by prenylamine.
active cellular reuptake of released noradrenaline,4 and this probably contributes to its antagonism of antihypertensive agents… Expand
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Highly Cited
1970
Highly Cited
1970
The effect of phospholipase A on the calcium transport and the role of unsaturated fatty acids in ATPase activity of sarcoplasmic vesicles.
1 The cleavage of the β-ester bond of the phospholipids in the membranes of the sarcoplasmic reticulum by phospholipase A… Expand
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Highly Cited
1967
Highly Cited
1967
Monoamines and their metabolites in the avian brain
1. In the avian brain, a high concentration of dopamine was found in a sharply contoured region of the nucleus basalis which may… Expand
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