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Precocious Puberty, Central

Known as: Central Precocious Puberty, Gonadotropin-Dependent Precocious Puberty 
Premature onset of sexual development triggered by the premature secretion of gonadotropins.(NICHD)
National Institutes of Health

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Broader (1)

Precocious Puberty

Papers overview

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Highly Cited
2016
Highly Cited
2016
Mutations in the maternally imprinted gene MKRN3 are common in familial central precocious puberty.
CONTEXT AND OBJECTIVE Idiopathic central precocious puberty (iCPP) is defined as early activation of the hypothalamic-pituitary… 
Highly Cited
2014
Highly Cited
2014
Central precocious puberty that appears to be sporadic caused by paternally inherited mutations in the imprinted gene makorin ring finger 3.
CONTEXT Loss-of-function mutations in makorin ring finger 3 (MKRN3), an imprinted gene located on the long arm of chromosome 15… 
Highly Cited
2012
Highly Cited
2012
Pathological and Incidental Findings on Brain MRI in a Single-Center Study of 229 Consecutive Girls with Early or Precocious Puberty
Central precocious puberty may result from organic brain lesions, but is most frequently of idiopathic origin. Clinical or… 
Highly Cited
2009
Highly Cited
2009
Adequacy of a Single Unstimulated Luteinizing Hormone Level to Diagnose Central Precocious Puberty in Girls
OBJECTIVE. Using basal specimens from original gonadotropin radioimmunoassays, it was not possible to differentiate prepuberty… 
Highly Cited
2003
Highly Cited
2003
Cranial MRI scans are indicated in all girls with central precocious puberty
Aims: (1) To assess the value of cranial magnetic resonance imaging (MRI) scans in the investigation of girls with central… 
Review
2001
Review
2001
Gonadotropin-releasing-hormone-receptor antagonists
Review
2000
Review
2000
Etiology and Age Incidence of Precocious Puberty in Girls: A Multicentric Study
We review the etiology and age incidence of precocious puberty in 438 girls examined between 1988-1998; 428 (97.7%) had central… 
Highly Cited
1999
Highly Cited
1999
Diagnostic value of fluorometric assays in the evaluation of precocious puberty.
To establish normative data and determine the value of fluorometric AutoDELFIA assays (Wallac Oy) in the investigation of… 
Highly Cited
1992
Highly Cited
1992
Magnetic resonance imaging in the diagnosis of growth hormone deficiency.
Highly Cited
1986
Highly Cited
1986
The NIH experience with precocious puberty: diagnostic subgroups and response to short-term luteinizing hormone releasing hormone analogue therapy.
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