Prazepam

A method was developed and fully validated for the quantitation of prazepam and its major metabolites, oxazepam and nordiazepam… (More)

A liquid chromatographic/mass spectrometric assay with atmospheric pressure chemical ionization (LC/APCI-MS) is presented for… (More)

UNLABELLED The efficacy of antidepressants is well established in major depressions, especially those with melancholic features… (More)

Thirty-nine healthy volunteers received single oral doses of either alprazolam (1 mg), lorazepam (2 mg), prazepam (20 mg), or… (More)

In a double-blind parallel-group pharmacokinetic and pharmacodynamic study, 31 healthy volunteers received single oral doses of… (More)

The biotransformation pathways following oral administration of prazepam are characterized. The time course of the active… (More)

A double-blind, random design, parallel group, four-week study of prazepam, diazepam, lorazepam, and placebo was conducted in… (More)

Our subjects were 15 young (aged 22 to 42 yr) and 14 elderly (aged 62 to 85 yr) people who took single oral doses of 20 mg… (More)

An original electron-capture gas chromatographic assay was developed for simultaneous measurement of plasma levels of the… (More)

A double-blind randomized multicenter parallel group comparison of prazepam in divided doses vs. placebo was conducted by 15… (More)