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Pralidoxime chloride

Known as: pyridine-2-aldoxime methachloride, 2-PAM chloride, 2 pam chloride 
National Institutes of Health

Related topics

Related topics

8 relations
Drug AllergyDrug OverdoseDrug toxicityPoisoning

Broader (2)

Pralidoxime Compoundspralidoxime

Narrower (2)

ProtopamProtopam Chloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Pro-2-PAM therapy for central and peripheral cholinesterases.
Highly Cited
2007
Highly Cited
2007
Anticonvulsants for Nerve Agent-Induced Seizures: The Influence of the Therapeutic Dose of Atropine
Two guinea pig models were used to study the anticonvulsant potency of diazepam, midazolam, and scopolamine against seizures… 
2002
2002
Lizard cholinesterases as biomarkers of pesticide exposure: Enzymological characterization
Here we report the results of a study conducted to elucidate the enzymological characteristics of lizard cholinesterases (ChEs… 
Highly Cited
1999
Highly Cited
1999
Anticonvulsant treatment of nerve agent seizures: anticholinergics versus diazepam in soman-intoxicated guinea pigs
Highly Cited
1992
Highly Cited
1992
Dizocilpine (MK-801) arrests status epilepticus and prevents brain damage induced by soman
Highly Cited
1992
Highly Cited
1992
Does pralidoxime affect outcome of management in acute organophosphorus poisoning?
Highly Cited
1990
Highly Cited
1990
Decreased brain pathology in organophosphate-exposed rhesus monkeys following benzodiazepine therapy
Highly Cited
1989
Highly Cited
1989
Atropine and/or diazepam therapy protects against soman-induced neural and cardiac pathology.
Review
1987
Review
1987
Therapeutic Dosing of Pralidoxime Chloride
Pralidoxime chloride is a useful agent in the treatment of organophosphate poisoning. Poisindex, a widely used poisoning… 
1973
1973
Effects of heat and exercise on the elimination of pralidoxime in man
Pralidoxime chloride, used clinically to reactivate cholinesterase in organophosphate poisoning, is rapidly eliminated by the… 
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