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Potassium Voltage-Gated Channel Subfamily KQT Member 1

Known as: KvLQT1, Voltage-Gated Potassium Channel Subunit Kv7.1, IKs Producing Slow Voltage-Gated Potassium Channel Subunit Alpha KvLQT1 
Potassium voltage-gated channel subfamily KQT member 1 (676 aa, ~75 kDa) is encoded by the human KCNQ1 gene. This protein is involved in cardiac… Expand
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
BACKGROUND Long-QT Syndrome (LQTS) is a cardiovascular disorder characterized by prolongation of the QT interval on ECG and… Expand
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Highly Cited
2000
Highly Cited
2000
The KvLQT1 gene encodes a voltage-gated potassium channel. Mutations in KvLQT1 underlie the dominantly transmitted Ward-Romano… Expand
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Highly Cited
2000
Highly Cited
2000
The aim of this study was to test the hypothesis that some cases of drug-induced arrhythmias depend on genetic predisposition… Expand
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Highly Cited
2000
Highly Cited
2000
The LQT1 locus (KCNQ1) has been correlated with the most common form of inherited long QT (LQT) syndrome. LQT patients suffer… Expand
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Highly Cited
1999
Highly Cited
1999
OBJECTIVES This study was performed to evaluate the QT interval and heart rate responses to exercise and recovery in gene and… Expand
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Highly Cited
1998
Highly Cited
1998
1. The time course and voltage dependence of inactivation of KvLQT1 channels expressed in Xenopus oocytes were studied using two… Expand
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Highly Cited
1998
Highly Cited
1998
The slowly activating delayed rectifier K+ current, IKs, is an important modulator of cardiac action potential repolarization… Expand
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Highly Cited
1997
Highly Cited
1997
The Jervell and Lange-Nielsen (JLN) syndrome (MIM 220400) is an inherited autosomal recessive disease characterized by a… Expand
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Highly Cited
1997
Highly Cited
1997
The clinical features of long QT syndrome result from episodic life-threatening cardiac arrhythmias, specifically the polymorphic… Expand
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Highly Cited
1996
Highly Cited
1996
The slowly activating delayed-rectifier K+ current, I(Ks), modulates the repolarization of cardiac action potentials. The… Expand
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