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Potassium Voltage-Gated Channel Subfamily KQT Member 1

Known as: KvLQT1, Voltage-Gated Potassium Channel Subunit Kv7.1, IKs Producing Slow Voltage-Gated Potassium Channel Subunit Alpha KvLQT1 
Potassium voltage-gated channel subfamily KQT member 1 (676 aa, ~75 kDa) is encoded by the human KCNQ1 gene. This protein is involved in cardiac… 
National Institutes of Health

Related topics

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18 relations
Cardiac Muscle ContractionCellular MembraneGated Ion ChannelHomo sapiens

Papers overview

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Highly Cited
2009
Highly Cited
2009
Patellofemoral arthroplasty: a multi-centre study with minimum 2-year follow-up
Recently, patellofemoral arthroplasty has attracted increased interest as a salvage treatment for isolated patellofemoral… 
Highly Cited
2004
Highly Cited
2004
KvLQT1 Modulates the Distribution and Biophysical Properties of HERG
Cardiac repolarization is under joint control of the slow (IKs) and rapid (IKr) delayed rectifier currents. Experimental and… 
Highly Cited
2000
Highly Cited
2000
Evidence for a Cardiac Ion Channel Mutation Underlying Drug‐Induced QT Prolongation and Life‐Threatening Arrhythmias
Ion Channel Mutations and Drug‐Induced TdP. The aim of this study was to test the hypothesis that some cases of drug‐induced… 
Highly Cited
2000
Highly Cited
2000
Mink Subdomains That Mediate Modulation of and Association with Kvlqt1
KvLQT1 is a voltage-gated potassium channel expressed in cardiac cells that is critical for myocardial repolarization. When… 
Highly Cited
1999
Highly Cited
1999
Sinus node function and ventricular repolarization during exercise stress test in long QT syndrome patients with KvLQT1 and HERG potassium channel defects.
Highly Cited
1999
Highly Cited
1999
Multipoint analysis of human chromosome 11p15/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation…
WT2 is defined by maternal-specific loss of heterozygosity (LOH) on chromosome 11p15.5 in Wilms' tumors (WTs). The imprinted H19… 
Highly Cited
1998
Highly Cited
1998
Activation and inactivation of homomeric KvLQT1 potassium channels.
Highly Cited
1998
Highly Cited
1998
Imprinting of mouse Kvlqt1 is developmentally regulated.
Mouse distal chromosome 7 contains a cluster of at least five imprinted genes. The syntenic region in humans, at 11p15.5, has… 
Highly Cited
1998
Highly Cited
1998
A Dominant Negative Isoform of the Long QT Syndrome 1 Gene Product*
Mutations in the KvLQT1 gene are the cause of the long QT syndrome 1. KvLQT1 gene product is associated with the regulator… 
Highly Cited
1997
Highly Cited
1997
KvLQT1, a voltage-gated potassium channel responsible for human cardiac arrhythmias.
The clinical features of long QT syndrome result from episodic life-threatening cardiac arrhythmias, specifically the polymorphic… 
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