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Position Effect Variegation

Cell to cell variation in gene expression caused by chromosomal position effects.
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Genes normally resident in euchromatic domains are silenced when packaged into heterochromatin, as exemplified in Drosophila… Expand
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Highly Cited
2000
Highly Cited
2000
mod(mdg4), also known as E(var)3-93D, is involved in a variety of processes, such as gene silencing in position effect… Expand
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Review
1997
Review
1997
Publisher Summary This chapter describes that the problems relating to the organization of heterochromatin are prominent in the… Expand
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Highly Cited
1996
Highly Cited
1996
Human CD2 locus control region (LCR) sequences are shown here to be essential for establishing an open chromatin configuration… Expand
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Highly Cited
1995
Highly Cited
1995
A euchromatic gene placed in the vicinity of heterochromatin by a chromosomal rearrangement generally exhibits position effect… Expand
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Review
1995
Review
1995
Heterochromatin is both necessary for the expression of heterochromatic genes and inhibitory for the expression of euchromatic… Expand
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Highly Cited
1994
Highly Cited
1994
Chromatin structure at Schizosaccharomyces pombe centromeres is unusual. The insertion of the ura4 gene within these centromeres… Expand
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Review
1992
Review
1992
Variegated phenotypes often result from chromosomal rearrangements that place euchromatic genes next to heterochromatin. In such… Expand
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Highly Cited
1989
Highly Cited
1989
Position effect variegation results from chromosome rearrangements which translocate euchromatic genes close to the… Expand
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Highly Cited
1988
Highly Cited
1988
Twelve dominant enhancers of position effect variegation, representing four loci on the second and third chromosomes of… Expand
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