Position Effect Variegation

Cell to cell variation in gene expression caused by chromosomal position effects.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2018
05101519742018

Papers overview

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2008
2008
Sequences proximal to transgene integration sites are able to deregulate transgene expression resulting in complex position… (More)
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Highly Cited
2004
Highly Cited
2004
Genes normally resident in euchromatic domains are silenced when packaged into heterochromatin, as exemplified in Drosophila… (More)
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2004
2004
Variations in compaction of chromosomal material of the rearrangements Dp(1;f) 1337, Dp(1;f) R, Dp(1;1)pn2b, and T(1;4)w m258-21… (More)
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2002
2002
Terminal deletions of a Drosophila minichromosome (Dp(1;f)1187) dramatically increase the position effect variegation (PEV) of a… (More)
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Highly Cited
1996
Highly Cited
1996
Human CD2 locus control region (LCR) sequences are shown here to be essential for establishing an open chromatin configuration… (More)
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Highly Cited
1995
Highly Cited
1995
A euchromatic gene placed in the vicinity of heterochromatin by a chromosomal rearrangement generally exhibits position effect… (More)
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Highly Cited
1994
Highly Cited
1994
Chromatin structure at Schizosaccharomyces pombe centromeres is unusual. The insertion of the ura4 gene within these centromeres… (More)
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1989
1989
Most variegating position effects are a consequence of placing a euchromatic gene adjacent to alpha-heterochromatin. In such… (More)
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Highly Cited
1988
Highly Cited
1988
Twelve dominant enhancers of position effect variegation, representing four loci on the second and third chromosomes of… (More)
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1983
1983
The histone genes of wild-type Drosophila melanogaster are reiterated 100-150 times per haploid genome and are located in the… (More)
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