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Position Effect Variegation

Cell to cell variation in gene expression caused by chromosomal position effects.
National Institutes of Health

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Chromosomal Position Effects

Papers overview

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2004
2004
Cytogenetic and molecular aspects of position effect variegation in Drosophila melanogaster
A new genetic model system for studying position effect variegation in Drosophila melanogaster was found. It allows the analysis… 
2002
2002
Loss of heterochromatin protein 1 (HP1) chromodomain function in mammalian cells by intracellular antibodies causes cell death.
The chromodomain (CD) is a highly conserved motif present in a variety of animal and plant proteins, and its probable role is to… 
Highly Cited
1999
Highly Cited
1999
Position effect variegation at the mating-type locus of fission yeast: a cis-acting element inhibits covariegated expression of genes in the silent and expressed domains.
Schizosaccharomyces pombe switches its mating type by transposing a copy of unexpressed genes from the respective mat2 or mat3… 
Review
1998
Review
1998
Polytene chromosomes, heterochromatin, and position effect variegation.
Review
1994
Review
1994
Position effect variegation in yeast.
Classically, position effect variegation has been studied in Drosophila and results when a euchromatic gene is placed adjacent to… 
1994
1994
Weakener of white (Wow), a gene that modifies the expression of the white eye color locus and that suppresses position effect variegation in Drosophila melanogaster.
A locus is described in Drosophila melanogaster that modifies the expression of the white eye color gene. This trans-acting… 
1992
1992
Protein phosphorylation is involved in the regulation of chromatin condensation during interphase
1991
1991
Cytogenetic and molecular aspects of position effect variegation in Drosophila
Variations in compaction of chromosomal material of the rearrangements Dp(1;f) 1337, Dp(1;f) R, Dp(1;1)pn2b, and T(1;4)wm258-21… 
Highly Cited
1989
Highly Cited
1989
Towards an understanding of position effect variegation.
Most variegating position effects are a consequence of placing a euchromatic gene adjacent to alpha-heterochromatin. In such… 
Review
1978
Review
1978
Mitotic recombination and position effect variegation.
Mitotic recombination and position effect variegation have widely different underlying mechanisms. 
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