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Polythiazide

Known as: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-2-methyl-3-(((2,2,2-trifluoroethyl)thio)methyl)-, 1,1-dioxide, Polythiazide [Chemical/Ingredient] 
A long acting benzothiadiazine sulfonamide derivative belonging to the class of the thiazide diuretics. Polythiazide is excreted mainly in its… Expand
National Institutes of Health

Papers overview

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Highly Cited
1984
Highly Cited
1984
The effects of prazosin and propranolol on total serum cholesterol concentration, low-density lipoprotein and high-density… Expand
Highly Cited
1983
Highly Cited
1983
M‐mode echocardiography has become a valuable tool in the evaluation of changes in left ventricular muscle mass during… Expand
Highly Cited
1981
Highly Cited
1981
Abstract Seven elderly patients were encountered who had been taking thiazides or thiazide-like diuretics (hydrochlorothiazide… Expand
1981
1981
A selective high-performance liquid chromatographic method has been developed for the determination of polythiazide in human… Expand
1978
1978
An assay for polythiazide, sufficiently sensitive to measure plasma concentrations of this high‐potency diuretic agent, has been… Expand
Highly Cited
1978
Highly Cited
1978
In a single-blind comparative study of the cases of 30 moderately hypertensive patients, clonidine hydrochloride and prazosin… Expand
Highly Cited
1972
Highly Cited
1972
Twenty-seven patients with severe hypertension were treated initially with propranolol alone, and polythiazide was later added… Expand
Highly Cited
1970
Highly Cited
1970
. Thirty-eight men with untreated essential hypertension in WHO stage 1 or II, aged 19–57 years, all working, have been studied… Expand
1962
1962
Summary The renal clearance of C14 labeled polythiazide, a new and highly potent diuretic agent, was studied in anesthetized dogs… Expand
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1961
1961
Summary Polythiazide was found to be a highly potent, orally active diuretic agent in rats and dogs. Duration of polythiazide… Expand
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