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Polyribonucleotide Nucleotidyltransferase 1, Mitochondrial

Known as: PNPase 1, Polynucleotide Phosphorylase 1, 3'-5' RNA Exonuclease OLD35 
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (783 aa, ~86 kDa) is encoded by the human PNPT1 gene. This protein is involved in the… 
National Institutes of Health

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3'-5'-ExonucleasesEnzyme GeneHomo sapiensPNPT1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Epigenetic modulation of β cells by interferon-α via PNPT1/mir-26a/TET2 triggers autoimmune diabetes.
Type 1 diabetes (T1D) is caused by autoimmune destruction of pancreatic β cells. Mounting evidence supports a central role for… 
2009
2009
Cloning, expression, purification and kinetics studies of the enzime polynucleotide phosphorylase (PNPase, EC 2.7.7.8) from Mycobacterium tuberculosis
Tuberculosis (TB) is the leading cause of death in the world due to infection with a single microbial agent, being mainly caused… 
Highly Cited
2004
Highly Cited
2004
AtmtPNPase is required for multiple aspects of the 18S rRNA metabolism in Arabidopsis thaliana mitochondria.
Plant mitochondria contain three rRNA genes, rrn26, rrn18 and rrn5, the latter two being co-transcribed. We have recently… 
Highly Cited
2000
Highly Cited
2000
Transcriptional and post‐transcriptional control of polynucleotide phosphorylase during cold acclimation in Escherichia coli
Polynucleotide phosphorylase (PNPase, polyribonucleotide nucleotidyltransferase, EC 2.7.7.8) is one of the cold shock‐induced… 
1986
1986
Nonisotopic detection methods for strand displacement assays of nucleic acids.
Using the enzymes terminal deoxyribonucleotidyltransferase (EC 2.7.7.31) and polynucleotide phosphorylase (EC 2.7.7.8), we… 
1984
1984
[Regulatory mutants for the synthesis of a 2d purine nucleoside phosphorylase in Escherichia coli K-12. I. Synthesis inducers and the substrate specificity of purine nucleoside phosphorylase in pndR…
Restoration of the ability to catabolise the purine nucleosides in phenotypic revertants of Escherichia coli K-12 mutants… 
1978
1978
[Destruction of mRNA poly-A sequences by polynucleotide phosphorylase in rat liver microsomes].
A possible role of polynucleotide phosphorylase (PNPase) in the destruction of poly-A fragments located at the 3'-OH end of mRNA… 
Highly Cited
1975
Highly Cited
1975
The fate of ribosomes in Escherichia coli cells starved for a carbon source.
Highly Cited
1975
Highly Cited
1975
Decay of ribosomal ribonucleic acid in Escherichia coli cells starved for various nutrients.
1971
1971
The effect of low concentrations of glutaraldehyde on Micrococcus lysodeikticus membranes: changes in the release of membrane-associated enzymes and membrane structure.
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