Polycystic kidney disease, type 2

Individuals who are at risk for autosomal dominant polycystic kidney disease are often screened by ultrasound using diagnostic… Expand

A number of inherited disorders result in renal cyst development. The most common form, autosomal dominant polycystic kidney… Expand

Mutation-based molecular diagnostics of autosomal dominant polycystic kidney disease (ADPKD) is complicated by genetic and… Expand

Drs Ganz and Vita 1 and Verma, Buchanan, and Anderson2 have presented persuasive evidence that endothelial function is… Expand

BACKGROUND Patients with autosomal dominant polycystic kidney disease (ADPKD) are at risk of developing intracranial aneurysms… Expand

The stereotyped mating behaviour of the Caenorhabditis elegans male is made up of several substeps: response, backing, turning… Expand

The function(s) of the genes (PKD1 and PKD2) responsible for the majority of cases of autosomal dominant polycystic kidney… Expand

Germline mutations in PKD2 cause autosomal dominant polycystic kidney disease. We have introduced a mutant exon 1 in tandem with… Expand

Autosomal dominant polycystic kidney disease (ADPKD) describes a group of at least three genetically distinct disorders with… Expand

PKD1 and PKD2 are two recently identified genes that are responsible for the vast majority of autosomal polycystic kidney disease… Expand