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Polycomb Repressive Complex 2
Known as:
Polycomb Repressive Complex 2 [Chemical/Ingredient]
A multisubunit polycomb protein complex that catalyzes the METHYLATION of chromosomal HISTONE H3. It works in conjunction with POLYCOMB REPRESSIVE…
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National Institutes of Health
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Related topics
Related topics
10 relations
In Blood
Process of secretion
agonists
antagonists & inhibitors
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Narrower (2)
Jarid2 protein, mouse
Phc2 protein, mouse
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Genomic targeting and function of polycomb repressive complex 2 and ISWI chromatin remodelers
D. Barisic
2017
Corpus ID: 90350453
In eukaryotes, chromatin provides a way to compact the genetic material into the confined space of a nucleus. It is also a means…
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2016
2016
An allosteric PRC 2 inhibitor targeting the H 3 K 27 me 3 binding pocket of EED
W. Qi
,
K. Zhao
,
+37 authors
E. Li
2016
Corpus ID: 465159
Wei Qi, Kehao Zhao, Justin Gu, Ying Huang, Youzhen Wang, Hailong Zhang, Maya Zhang, Jeff Zhang, Zhengtian Yu, Ling Li, Lin Teng…
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2016
2016
An Analysis of Polycomb Repressive Complex 2 Function Through Imprinted Mouse X-chromosome Inactivation.
Michael Hinten
2016
Corpus ID: 100099718
Proper embryonic development requires the intricate modulation of gene expression states, controlled in part by the cellular…
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2015
2015
MicroRNA-1955 p acts as an anti-oncogene by targeting PHF 19 in hepatocellular carcinoma
X. Hui
,
Yan-Wei Hu
,
+11 authors
Qian Wang
2015
Corpus ID: 30447854
Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide. PHD finger protein 19 (PHF19) encodes a member of…
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Review
2015
Review
2015
Epigenetics in Cancer Metastasis
Weijing Xu
2015
Corpus ID: 31309066
Cancer has been traditionally regarded as a disease caused by genetic mutations. However, since the development of epigenetic and…
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2014
2014
Herz chromatin signaling Histone H 3 lysine-to-methionine mutants as a paradigm to study
Hans-Martin Herz
,
M. Morgan
,
+6 authors
J. C. Eissenberg
2014
Corpus ID: 207777839
, 1065 (2014); 345 Science et al. Hans-Martin Herz chromatin signaling Histone H3 lysine-to-methionine mutants as a paradigm to…
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2013
2013
Promoter histone H 3 K 27 methylation in the control of IGF 2 imprinting in human tumor cell lines
Tao Li
,
Hui-Ling Chen
,
+5 authors
Ji-Fan Hu
2013
Corpus ID: 85449911
Aberrant imprinting of the insulin-like growth factor II (IGF2) gene is a molecular hallmark of many tumors. Reactivation of the…
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2012
2012
MiR-137 is epigenetically silenced in MYCN amplified neuroblastomas and targets the polycomb repressive complex 2 (PRC2) component EZH2
Anneleen Beckers
,
M. Ongenaert
,
+6 authors
K. De Preter
2012
Corpus ID: 87846697
2012
2012
Polycomb stations Spreading of X chromosome inactivation via a hierarchy of defined Material Supplemental
Stefan F. Pinter
,
Ruslan I. Sadreyev
,
+4 authors
Jeannie T. Lee
2012
Corpus ID: 207763003
Material Supplemental http://genome.cshlp.org/content/suppl/2012/08/01/gr.133751.111.DC1.html References http://genome.cshlp.org…
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2010
2010
DETERMINATION OF THE FCS DOMAIN OF POLYCOMB REPRESSIVE COMPLEX 1 FROM DROSOPHILA MELANOGASTER
C. Tong
2010
Corpus ID: 31228346
Polycomb group (PcG) proteins play an important regulatory role in gene expression. These proteins are crucial in stem cell…
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