Polycomb Repressive Complex 2

Known as: Polycomb Repressive Complex 2 [Chemical/Ingredient] 
A multisubunit polycomb protein complex that catalyzes the METHYLATION of chromosomal HISTONE H3. It works in conjunction with POLYCOMB REPRESSIVE… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2018
0204020042018

Papers overview

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Highly Cited
2014
Highly Cited
2014
G9a/GLP and Polycomb Repressive Complex 2 (PRC2) are two major epigenetic silencing machineries, which in particular methylate… (More)
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Highly Cited
2013
Highly Cited
2013
Polycomb repressive complex 2 (PRC2) is a histone methyltransferase required for epigenetic silencing during development and… (More)
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Highly Cited
2012
Highly Cited
2012
Polycomb Repressive Complex 2 (PRC2) is essential for gene silencing, establishing transcriptional repression of specific genes… (More)
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Highly Cited
2012
Highly Cited
2012
T cell acute lymphoblastic leukemia (T-ALL) is an immature hematopoietic malignancy driven mainly by oncogenic activation of… (More)
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Highly Cited
2012
Highly Cited
2012
Pluripotent cells possess the ability to differentiate into any cell type. Commitment to differentiate into specific lineages… (More)
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Highly Cited
2011
Highly Cited
2011
Polycomb repressive complex 2 (PRC2) is a key regulator of epigenetic states catalyzing histone H3 lysine 27 trimethylation… (More)
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Highly Cited
2008
Highly Cited
2008
Vernalization, the acceleration of flowering by winter, involves cold-induced epigenetic silencing of Arabidopsis FLC. This… (More)
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Highly Cited
2008
Highly Cited
2008
Polycomb repressive complex 2 (PRC2) methylates histone H3 tails at lysine 27 and is essential for embryonic development. The… (More)
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Highly Cited
2008
Highly Cited
2008
Polycomb group (PcG) proteins are evolutionarily conserved in animals and plants, and play critical roles in the regulation of… (More)
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Highly Cited
2008
Highly Cited
2008
Polycomb group proteins are transcriptional repressors that play a central role in the establishment and maintenance of gene… (More)
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