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Polycomb Repressive Complex 2
Known as:
Polycomb Repressive Complex 2 [Chemical/Ingredient]
A multisubunit polycomb protein complex that catalyzes the METHYLATION of chromosomal HISTONE H3. It works in conjunction with POLYCOMB REPRESSIVE…
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National Institutes of Health
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Related topics
Related topics
10 relations
In Blood
Process of secretion
agonists
antagonists & inhibitors
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Narrower (2)
Jarid2 protein, mouse
Phc2 protein, mouse
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Bisthioether Stapled Peptides Targeting Polycomb Repressive Complex 2 Gene Repression
Gan Zhang
2019
Corpus ID: 92846047
Interactions between proteins play a key role in nearly all cellular process, and therefore, disruption of such interactions may…
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2016
2016
An allosteric PRC 2 inhibitor targeting the H 3 K 27 me 3 binding pocket of EED
W. Qi
,
Kehao Zhao
,
+37 authors
E. Li
2016
Corpus ID: 465159
Wei Qi, Kehao Zhao, Justin Gu, Ying Huang, Youzhen Wang, Hailong Zhang, Maya Zhang, Jeff Zhang, Zhengtian Yu, Ling Li, Lin Teng…
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2016
2016
Chronic Myelogenous Leukemia – Initiating Cells Require Polycomb Group Protein EZH 2
Huafeng Xie
,
Cong Peng
,
+11 authors
S. Orkin
2016
Corpus ID: 32565782
1 Division of Hematology/Oncology, Boston Children’s Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute…
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2016
2016
DNA methylation reactivates GAD1 expression in cancer by preventing CTCF-mediated polycomb repressive complex 2 recruitment
H. Yan
,
G. Tang
,
+6 authors
S. Sun
Oncogene
2016
Corpus ID: 2301233
2015
2015
MicroRNA-1955 p acts as an anti-oncogene by targeting PHF 19 in hepatocellular carcinoma
X. Hui
,
Huang Yan-wei
,
+11 authors
Qian Wang
2015
Corpus ID: 30447854
Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide. PHD finger protein 19 (PHF19) encodes a member of…
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2015
2015
Tumour Survival Signals and Epigenetic Gene Silencing in Multiple Myeloma : Implications for Biology and Therapy
Charlotte Fristedt Duvefelt
2015
Corpus ID: 82924283
This thesis is focused on multiple myeloma (MM), a haematological malignancy that still remains incurable. The pathogenesis of MM…
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Review
2014
Review
2014
Polycomb group genes as the key regulators in gene silencing
Shuaikun Su
,
M. Zhang
,
Lian-Yun Li
,
Min Wu
Wuhan University Journal of Natural Sciences
2014
Corpus ID: 16518994
The Polycomb group (PcG) genes repress gene expression mainly through chromatin modifications and regulation of chromatin…
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2013
2013
Epigenetics: Methylation reboot
Sarah E. Seton-Rogers
Nature Reviews. Cancer
2013
Corpus ID: 1154818
The contribution of epigenetic changes to malignant behaviour has been investigated using induced pluripotent stem cell (iPSC…
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2012
2012
Polycomb stations Spreading of X chromosome inactivation via a hierarchy of defined Material Supplemental
Stefan F. Pinter
,
R. Sadreyev
,
+4 authors
Jeannie T. Lee
2012
Corpus ID: 207763003
Material Supplemental http://genome.cshlp.org/content/suppl/2012/08/01/gr.133751.111.DC1.html References http://genome.cshlp.org…
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2010
2010
DETERMINATION OF THE FCS DOMAIN OF POLYCOMB REPRESSIVE COMPLEX 1 FROM DROSOPHILA MELANOGASTER
C. Tong
2010
Corpus ID: 31228346
Polycomb group (PcG) proteins play an important regulatory role in gene expression. These proteins are crucial in stem cell…
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