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Piromidic Acid

Known as: Acid, Piromidic, Piromidic Acid [Chemical/Ingredient], Pyrido(2,3-d)pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-pyrrolidinyl)- 
A quinolone antibiotic with activity against gram-negative bacteria. Piromidic acid is used in the treatment of urinary tract and intestinal… 
National Institutes of Health

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9 relations

Broader (2)

Anti-Infective AgentsAnti-Infective Agents, Urinary
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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2008
2008
[Acute interstitial nephritis caused by drugs].
Within 30 months the diagnosis of drug-induced acute interstitial nephritis was made in ten patients with acute onset of renal… 
2005
2005
Piromidic acid and its ethylic ester: Absorption, distribution, excretion
The absorption, distribution and excretion of piromidic acid and its ethyl ester were investigated in the rat. When administered… 
1987
1987
Adhesive properties of Proteus genus related to antimicrobial agents resistance.
The in vitro attachment of 49 Proteus spp. to human urinary tract epithelial cells was determined. The antibacterial spectrum to… 
1984
1984
Researches on antibacterial and antifungal agents. II - Synthesis of 1-ethyl-1,4-dihydro-4-oxo-7-(1-pyrrolidinyl)quinoline-3-carboxylic acid, a novel highly active, broad-spectrum antibacterial agent…
The synthesis and antibacterial activities of 1-ethyl-1,4-dihydro-4-oxo-7-(1-pyrrolidinyl)quinoline-3-carboxylic acid are… 
1982
1982
Acute renal failure and piromidic acid.
A case of nonoliguric acute renal failure after treatment with piromidic acid and acetylsalicylic acid is reported. The… 
1980
1980
Pyrido[2,3-d]pyrimidine antibacterial agents. IV. Synthesis of metabolites of piromidic acid.
Three metabolites of the antibacterial agent, piromidic acid (8-ethyl-5, 8-dihydro-5-oxo-2-(1-pyrrolidinyl) pyrido [2, 3-d… 
1976
1976
Metabolism in rats and man of piromidic acid, a new antibacterial agent.
1. Metabolism of the antibacterial, piromidic acid (5,8-dihydro-8-ethyl-5-oxo-2-pyrrolidinopyrido[2,3-d]pyrimidine-6-carboxylic… 
1976
1976
Metabolism of piromidic acid, a new antibacterial agent. II. In vitro metabolic pathway of piromidic acid in rats.
The metabolism of piromidic acid (PA, 5, 8-dihydro-8-ethyl-5-oxo-2-pyrrolidinopyrido [2, 3-d] pyrimidine-6-carboxylic acid… 
1976
1976
Metabolism of piromidic acid, a new antibacterial agent. III. Determination of piromidic acid and its metabolites in blood, urine and bile of rats and humans.
The chemical determinations of piromidic acid (PA, 5, 8-dihydro-8-ethyl-5-oxo-2-pyrrolidinopyrido [2, 3-d] pyrimidine-6… 
1976
1976
Metabolism of piromidic acid, a new antibacterial agent. V. Pharmacokinetics of priomidic acid in humans.
The pharmacokinetic studies of piromidic acid (PA, 5, 8-dihydro-8-ethyl-5-oxo-2-pyrrolidinopyrido [2, 3-d] pyrimidine-6…