Piperacillin

Known as: Piperacillinum, Pipercillin, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((((4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)phenylacetyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta(S*)))- 
A broad-spectrum semisynthetic, ampicillin-derived ureidopenicillin antibiotic. Piperacillin binds to penicillin binding proteins (PBP), the enzymes… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
BACKGROUND Piperacillin-tazobactam is frequently used to treat Pseudomonas aeruginosa infections in critically ill patients. In… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Diabetic foot infections are a common and serious problem, yet few randomised trials of adequate quality have compared… (More)
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Highly Cited
2004
Highly Cited
2004
At the bone marrow transplantation center of the San Martino Hospital (Genoa), we observed an increase in the rate of patients… (More)
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Highly Cited
2002
Highly Cited
2002
We sought to determine the epidemiological characteristics of patients in an intensive care unit (ICU) who developed ventilator… (More)
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Highly Cited
2001
Highly Cited
2001
There is little information about the clinical effectiveness of cefepime and piperacillin-tazobactam in the treatment of… (More)
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Highly Cited
1995
Highly Cited
1995
Gram-positive bacteria have become the predominant infecting organisms in granulocytopenic cancer patients. Empiric antibiotic… (More)
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Highly Cited
1994
Highly Cited
1994
The rapid, empiric institution of broad-spectrum antibacterial therapy for the febrile, neutropenic patient has had a profound… (More)
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Highly Cited
1992
Highly Cited
1992
Pseudomonas aeruginosa 579 biofilms formed on dialysis membranes retarded piperacillin diffusion. Treatment of biofilms with 5.0… (More)
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Highly Cited
1988
Highly Cited
1988
Before 1985 at the Pitié-Salpêtrière Hospital in Paris (2,400 beds), resistance to cefotaxime in clinical isolates of… (More)
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Highly Cited
1984
Highly Cited
1984
The prevalence of Pseudomonas cepacia infection increased from 10% in 1971 to 18% by 1981 in a population of approximately 500… (More)
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