Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Picrotoxin

Known as: picrotoxins, 3,6-Methano-8H-1,5,7-trioxacyclopenta(ij)cycloprop(a)azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8aS*,8bbeta,9S*))-, compd. with (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8aS*,8, 3,6-Methano-8H-1,5,7-trioxacyclopenta(ij)cycloprop(a)azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8aS*,8bbeta,9S*))-, compd. with (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8aS*,8bbeta,9R*))-hexahydro-2a-hydroxy-8b-methyl-9-(1-methylethenyl)-3,6-methano-8H-1,5,7-trioxacyclopenta(ij)cycloprop(a)azulene-4,8(3H)-dione (1:1) 
A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
&NA; Colloidal systems based on lipids have attracted attention during the last two decades as a delivery method of drugs that… Expand
  • table 2-1
  • figure 2-1
  • figure 2-2
  • table 2-2
  • table 2-3
Review
2018
Review
2018
Natural resources continue to be an invaluable source of new, novel chemical entities of therapeutic utility due to the vast… Expand
  • figure 1
Review
2018
Review
2018
D-ɑ-tocopheryl polyethylene glycol succinate (Vitamin E TPGS or TPGS) has been approved by FDA as a safe adjuvant and widely used… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Review
2017
Review
2017
Preamble Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific… Expand
  • table 1
  • table 2
  • table 3
  • table 5
  • table 6
Review
2017
Review
2017
&NA; Anticancer therapy has always been a vital challenge for the development of nanomedicine. Repeated single therapeutic agent… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Review
2017
Review
2017
Jonathan L. Halperin, MD, FACC, FAHA, Chair Glenn N. Levine, MD, FACC, FAHA, Chair-Elect Sana M. Al-Khatib, MD, MHS, FACC… Expand
  • table 1
  • table 2
  • table 3
  • table 3
  • table 5
Highly Cited
2008
Highly Cited
2008
  • Zhuang Liu, K. Chen, +4 authors H. Dai
  • Cancer research
  • 2008
  • Corpus ID: 1910666
Chemically functionalized single-walled carbon nanotubes (SWNT) have shown promise in tumor-targeted accumulation in mice and… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Review
2008
Review
2008
  • Z. Zhao
  • Progress in Neurobiology
  • 2008
  • Corpus ID: 12354706
Acupuncture has been accepted to effectively treat chronic pain by inserting needles into the specific "acupuncture points… Expand
  • figure 1
  • figure 2
  • figure 3
Highly Cited
2005
Highly Cited
2005
PURPOSE The primary aim of National Surgical Adjuvant Breast and Bowel Project (NSABP) B-28 was to determine whether four cycles… Expand
Highly Cited
2004
Highly Cited
2004
  • R. Lister
  • Psychopharmacology
  • 2004
  • Corpus ID: 3329866
To investigate whether an elevated plus-maze consisting of two open and two closed arms could be used as a model of anxiety in… Expand
  • table 2
  • table 3
  • table 4
  • figure 1
  • figure 2