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Picoplatin

Known as: Platinum, Amminedichloro(2-methylpyridine)-, (SP-4-3), Cis-Amminedichloro (2-Methylpyridine) Platinum, Platinum, Amminedichloro(2-methylpyridine)-, (SP-4-3)- 
A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance… 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (2)

AMD 473ZD 0473
JM-473

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Chemotherapy, chemoresistance and the changing treatment landscape for NSCLC.
  • A. Chang
  • Lung cancer
  • 2011
  • Corpus ID: 20309798
Review
2011
Review
2011
Platinum anticancer drugs. From serendipity to rational design.
  • C. Monneret
  • Annales pharmaceutiques francaises
  • 2011
  • Corpus ID: 42607925
Review
2011
Review
2011
Current management of small cell lung cancer.
Highly Cited
2010
Highly Cited
2010
The status of platinum anticancer drugs in the clinic and in clinical trials.
Since its approval in 1979 cisplatin has become an important component in chemotherapy regimes for the treatment of ovarian… 
Highly Cited
2010
Highly Cited
2010
Organic Cation Transporters Modulate the Uptake and Cytotoxicity of Picoplatin, a Third-Generation Platinum Analogue
Picoplatin, a third-generation platinum agent, is efficacious against lung cancers that are otherwise resistant or become… 
Review
2010
Review
2010
A better platinum-based anticancer drug yet to come?
In attempts to overcome the drawbacks of cisplatin - severe toxicity, drug resistance and poor oral bioavailability - the… 
Highly Cited
2009
Highly Cited
2009
Phase II study of picoplatin as second-line therapy for patients with small-cell lung cancer.
PURPOSE This study was designed to confirm the efficacy and safety of picoplatin, a cisplatin analog designed to overcome… 
Review
2007
Review
2007
The resurgence of platinum-based cancer chemotherapy
  • L. Kèlland
  • Nature Reviews Cancer
  • 2007
  • Corpus ID: 205468214
The accidental discovery of the anticancer properties of cisplatin and its clinical introduction in the 1970s represent a major… 
Highly Cited
2006
Highly Cited
2006
Gateways to clinical trials.
Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the… 
Review
2000
Review
2000
Modulation of the chemical and biological properties of trans platinum complexes: monofunctional platinum complexes containing one nucleobase as potential antiviral chemotypes
Abstract. Replacement of one of the chloride leaving groups in trans-[PtCl2(NH3)(L)] by the nucleobase 9-ethylguanine gives the… 
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