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Picoplatin

Known as: Platinum, Amminedichloro(2-methylpyridine)-, (SP-4-3), Cis-Amminedichloro (2-Methylpyridine) Platinum, Platinum, Amminedichloro(2-methylpyridine)-, (SP-4-3)- 
A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
  • C. Monneret
  • Annales pharmaceutiques francaises
  • 2011
  • Corpus ID: 42607925
Review
2011
Review
2011
Highly Cited
2010
Highly Cited
2010
Since its approval in 1979 cisplatin has become an important component in chemotherapy regimes for the treatment of ovarian… 
Highly Cited
2010
Highly Cited
2010
Picoplatin, a third-generation platinum agent, is efficacious against lung cancers that are otherwise resistant or become… 
Review
2010
Review
2010
In attempts to overcome the drawbacks of cisplatin - severe toxicity, drug resistance and poor oral bioavailability - the… 
Highly Cited
2009
Highly Cited
2009
PURPOSE This study was designed to confirm the efficacy and safety of picoplatin, a cisplatin analog designed to overcome… 
Review
2007
Review
2007
  • L. Kèlland
  • Nature Reviews Cancer
  • 2007
  • Corpus ID: 205468214
The accidental discovery of the anticancer properties of cisplatin and its clinical introduction in the 1970s represent a major… 
Highly Cited
2006
Highly Cited
2006
Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the… 
Review
2000
Review
2000
Abstract. Replacement of one of the chloride leaving groups in trans-[PtCl2(NH3)(L)] by the nucleobase 9-ethylguanine gives the…