Picoplatin

Known as: Platinum, Amminedichloro(2-methylpyridine)-, (SP-4-3), Cis-Amminedichloro (2-Methylpyridine) Platinum, Platinum, Amminedichloro(2-methylpyridine)-, (SP-4-3)- 
A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2018
02420072018

Papers overview

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2016
2016
For the first time, the effects of picoplatin on the structure and esterase-like catalytic activity of human serum albumin (HSA… (More)
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Review
2013
Review
2013
INTRODUCTION Picoplatin was developed as platinum coordination complex to overcome development of resistance, through conjugation… (More)
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2012
2012
Oxaliplatin, satraplatin, and picoplatin are cisplatin analogs that interact with DNA forming intrastrand and interstrand DNA… (More)
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2012
2012
Picoplatin is a sterically hindered mononuclear platinum drug undergoing clinical trials. The 2-methylpyridine ring provides… (More)
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2010
2010
Picoplatin, a third-generation platinum agent, is efficacious against lung cancers that are otherwise resistant or become… (More)
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Highly Cited
2010
Highly Cited
2010
Since its approval in 1979 cisplatin has become an important component in chemotherapy regimes for the treatment of ovarian… (More)
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2010
2010
Picoplatin is a new generation platinum designed to overcome platinum resistance. The goal of this study was to assess picoplatin… (More)
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2010
2010
PURPOSE Dichloroacetate (DCA) inhibits pyruvate dehydrogenase kinase (PDK), and thus promotes glucose oxidation over glycolysis… (More)
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2009
2009
PURPOSE This study was designed to confirm the efficacy and safety of picoplatin, a cisplatin analog designed to overcome… (More)
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Review
2007
Review
2007
The three platinum-containing drugs that have been thus far approved by the FDA - cisplatin, carboplatin and oxaliplatin - have… (More)
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