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Picoplatin

Known as: Platinum, Amminedichloro(2-methylpyridine)-, (SP-4-3), Cis-Amminedichloro (2-Methylpyridine) Platinum, Platinum, Amminedichloro(2-methylpyridine)-, (SP-4-3)- 
A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance… 
National Institutes of Health

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AMD 473ZD 0473
JM-473

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
USE OF PICOPLATIN TO TREAT COLORECTAL CANCER
  • 2017
  • Corpus ID: 55311039
278. Picoplatin (SP-4-3) (cis-aminedichloro(2-methylpyridine) Pt(II)), and useful prodrugs and analogs thereofare disclosed in U… 
2013
2013
A bromine analogue of picoplatin: a new substance from the group of platinum-based chemotherapeutics.
A new substance, cis-amminedibromido(2-methylpyridine-κN)platinum(II), cis-[PtBr2(C6H7N)(NH3)], which is a potential platinum… 
2013
2013
Drugs in Clinical Development for Lung Cancer: Summary and Table
2013
2013
A New Synthetic Method of Picoplatin,An Antitumor Drug
To synthesize a platinum-based anti-tumor drug picoplatin, the key intermediate K[Pt(NH3)Cl3], synthesized from ammonium acetate… 
2009
2009
Use of picoplatin and bevacizumab for the treatment of colorectal cancer
The present invention provides a method of treating in various treatment regimens, metastatic colorectal cancer by the… 
2008
2008
Oral formulations for picoplatin
Picoplatin, including malignant tumors expressing resistance to premature organic platinum-based drugs such as cisplatin and… 
2008
2008
Final results of a phase I study of picoplatin and pegylated liposomal doxorubicin in advanced solid tumor malignancies
2568 Background: Picoplatin is a novel, sterically hindered platinum(II) complex designed to circumvent mechanisms of platinum… 
2008
2008
A phase II study of picoplatin with docetaxel and prednisone in chemotherapy-naive patients with metastatic hormone refractory prostate cancer (HRPC)
5153 Background: Picoplatin(Pico) is a platinum therapy specifically designed to overcome platinum resistance and to improve… 
2007
2007
A phase II study of picoplatin (pico) as second-line therapy for patients (pts) with small cell lung cancer (SCLC) who have resistant or refractory disease or have relapsed within 180 days of…
7722 Background: Pico is a sterically hindered plat analogue designed to overcome plat resistance with improved safety and… 
Review
2000
Review
2000
Modulation of the chemical and biological properties of trans platinum complexes: monofunctional platinum complexes containing one nucleobase as potential antiviral chemotypes
Abstract. Replacement of one of the chloride leaving groups in trans-[PtCl2(NH3)(L)] by the nucleobase 9-ethylguanine gives the… 
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