Phosphotyrosine

Known as: Tyrosine O phosphate, Phosphotyrosine [Chemical/Ingredient], L-tyrosine, dihydrogen phosphate (ester) 
An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1941-2018
010020030019412017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Tyrosine phosphorylation controls many cellular functions. Yet the three-part toolkit that regulates phosphotyrosine signaling… (More)
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Highly Cited
2008
Highly Cited
2008
Growth factors stimulate cells to take up excess nutrients and to use them for anabolic processes. The biochemical mechanism by… (More)
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Highly Cited
2004
Highly Cited
2004
To study the global dynamics of phosphotyrosine-based signaling events in early growth factor stimulation, we developed a mass… (More)
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Highly Cited
2004
Highly Cited
2004
Somatic mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR) gene are reportedly… (More)
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Highly Cited
2003
Highly Cited
2003
The c-Abl tyrosine kinase is inhibited by mechanisms that are poorly understood. Disruption of these mechanisms in the Bcr-Abl… (More)
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Highly Cited
2001
Highly Cited
2001
PD-1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily and contains two tyrosine residues in the… (More)
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Highly Cited
1993
Highly Cited
1993
Regulation of cell proliferation, differentiation, and metabolic homeostasis is associated with the phosphorylation and… (More)
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Highly Cited
1993
Highly Cited
1993
There are two major isoforms of the angiotensin II receptor, type 1 (AT1) and type 2 (AT2). AT2 is distinguished from AT1 with… (More)
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Highly Cited
1993
Highly Cited
1993
Interferon-gamma (IFN-gamma) stimulates transcription of specific genes by inducing tyrosine phosphorylation of a 91-kilodalton… (More)
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Highly Cited
1980
Highly Cited
1980
Epidermal growth factor (EGF)-enhanced protein kinase activity in plasma membrane preparations of A-431 human epidermoid… (More)
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