Phosphoribosylpyrophosphate synthetase
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1. The synthesis of nicotinamide-adenine dinucleotide from nicotinamide and nicotinic acid was compared over different time…
Complementary DNA clones for phosphoribosylpyrophosphate synthetase subunits I and II (PRS I and PRS II) were used to determine…
Two male patients with urate overexcretion and clinical gout in a family showed activity of phosphoribosylpyrophosphate (PRPP…
Sixty-eight independent hybrid clones were isolated after irradiated normal human lymphocytes were fused with Chinese hamster…
The activity of phosphoribosylpyrophosphate synthetase and the rate of phosphoribosylpyrophosphate accumulation are significantly…
A clone of cells in which the regulation of purine metabolism is genetically altered was selected and isolated from chemically…
Among affected members of a family (B. family) with excessive purine production and gout, activity of phosphoribosylpyrophosphate…
Abstract Human PP-ribose-P synthetase, partially purified from erythrocytes, was found to have Michaelis constants for ribose-5-P…
Abstract An analysis of the kinetic mechanism of phosphoribosylpyrophosphate (PRPP) synthetase has been carried out with highly…
Abstract A procedure is described for a 450-fold purification of 5-phosphoribosyl α-1-pyrophosphate (PRPP) synthetase from cells…