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Phosphoribosylpyrophosphate synthetase
Papers overview
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2007
2007
Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site.
PRPP (phosphoribosylpyrophosphate) is an important metabolite essential for nucleotide synthesis and PRS (PRPP synthetase… Expand
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Review
2005
Review
2005
The disorders of purine and pyrimidine metabolism are unusual in their variety of clinical presentations and in the mechanisms by… Expand
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1995
1995
The genetic and functional basis of phosphoribosylpyrophosphate synthetase (PRS) superactivity associated with purine nucleotide… Expand
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1988
1988
PURPOSE
Superactivity of 5-phosphoribosyl 1-pyrophosphate (PP-Rib-P) synthetase, inherited as an X chromosome-linked trait, has… Expand
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1975
1975
We have reported previously two siblings with gout and uric acid lithiasis associated with excessive purine production. In the… Expand
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1973
1973
Abstract A mutant phosphoribosylpyrophosphate synthetase was found in the erythrocytes of a gouty subject with excessive purine… Expand
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1973
1973
In hemolyzates from red cells of two brothers with purine overproduction and gout, activity of phosphoribosylpyrophosphate… Expand
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1973
1973
Abstract Phosphoribosylpyrophosphate (PRPP) synthetase participates in the biosynthesis in bacteria of purine nucleotides… Expand
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1972
1972
Abstract Human PP-ribose-P synthetase, partially purified from erythrocytes, was found to have Michaelis constants for ribose-5-P… Expand
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1971
1971
Abstract Phosphoribosylpyrophosphate (PP-ribose-P) synthetase was found to be distributed in all human tissues assayed and has… Expand
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