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Phosphonoformate

National Institutes of Health

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Papers overview

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1992
1992
DNA chain termination activity and inhibition of human immunodeficiency virus reverse transcriptase by carbocyclic 2',3'-didehydro-2',3'-dideoxyguanosine triphosphate.
Highly Cited
1989
Highly Cited
1989
Recombinant HIV-1 reverse transcriptase: purification, primary structure, and polymerase/ribonuclease H activities.
Highly Cited
1988
Highly Cited
1988
Studies on the mechanism of human immunodeficiency virus reverse transcriptase. Steady-state kinetics, processivity, and polynucleotide inhibition.
1988
1988
Treatment of cytomegalovirus disease.
Highly Cited
1980
Highly Cited
1980
Pyrophosphate analogues as inhibitors of herpes simplex virus type 1 DNA polymerase.
Highly Cited
1980
Highly Cited
1980
Reversible inhibition of cytomegalovirus replication by phosphonoformate.
Cytomegalovirus (CMV Ad. 169)-induced late antigens are specifically inhibited by phosphonoformate (PFA). Four fresh isolates of… 
Highly Cited
1979
Highly Cited
1979
Phosphonoformate inhibits reverse transcriptase.
The new antiviral substance phosphonoformate (PFA) has been tested in a cell-free system for its effect on reverse transcriptases… 
1979
1979
Inhibition of cytomegalovirus late antigens by phosphonoformate.
Phosphonoformate (PFA) at a concentration of 500 muM and higher completely inhibited the replication of cytomegalovirus (CMV) in… 
1979
1979
Phosphonoformate inhibition of visna virus replication
Phosphonoformate (PFA) inhibits multiplication of visna virus in sheep choroid plexus cells; a 50% reduction of virus yield was… 
Highly Cited
1978
Highly Cited
1978
Treatment of Experimental Herpesvirus Infections with Phosphonoformate and Some Comparisons with Phosphonoacetate
Phosphonoformate (PF) at a concentration of 5 to 10 μg/ml inhibited the growth of type 1 strains of herpes simplex virus (HSV) in… 
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