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Phosphatidylinositol N-Acetylglucosaminyltransferase Subunit A

Known as: Phosphatidylinositol-Glycan Biosynthesis Class A Protein, Phosphatidylinositol Glycan Anchor Biosynthesis, Class A, GlcNAc-PI Synthesis Protein 
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (484 aa, ~54 kDa) is encoded by the human PIGA gene. This protein is involved in the… 
National Institutes of Health

Related topics

Related topics

10 relations
Carbohydrate MetabolismEndoplasmic ReticulumEnzyme GeneGlycosyltransferase Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Characterisation of the enzymatic complex for the first step in glycosylphosphatidylinositol biosynthesis.
2000
2000
Effects of mutant PIG-A on gene expression
1997
1997
Genotypic and phenotypic implications in paroxysmal nocturnal hemoglobinuria (PNH): a preliminary investigation.
The genetic and biochemical defects underlying paroxysmal nocturnal hemoglobinuria (PNH) have recently been elucidated. The… 
1997
1997
Recurrent PIG‐A mutation (IVS5+1G→A) in a paediatric case of paroxysmal nocturnal haemoglobinuria: detection by the protein truncation test
Paroxysmal nocturnal haemoglobinuria (PNH) is an acquired haemopoietic stem cell disorder caused by the absence of glycosyl… 
Highly Cited
1995
Highly Cited
1995
Heterogeneous PIG-A mutations in different cell lineages in paroxysmal nocturnal hemoglobinuria.
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal defect of hematopoietic stem cells in which affected cells are… 
1995
1995
PIG‐A, DAF and proto‐oncogene expression in paroxysmal nocturnal haemoglobinuria‐associated acute myelogenous leukaemia blasts
Failed surface expression of the complement decay-accelerating factor (DAF) due to mutation of the PIG-A gene is a hallmark of… 
1995
1995
Identification of a PIG-A related processed gene on chromosome 12
PIG-A, the gene encoding the glycoinositol phospholipid anchor synthetic element that is defective in paroxysmal nocturnal… 
1995
1995
Cloning and characterization of the mouse PIG-A gene.
Review
1995
Review
1995
Characterization of the murine PIG-A promoter region high constitutive PIG-A gene expression in brain.
PIG-A is an X-linked gene that encodes a synthetic element required to initiate glycoinositol phospholipid (GPI) anchor assembly… 
1995
1995
PIG-A gene abnormalities in Thai patients with paroxysmal nocturnal hemoglobinuria.
Deficient biosynthesis of the glycosyl phosphatidyl inositol (GPI)-anchor in blood cells is implicated in the pathogenesis of… 
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