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Phosphaplatin PT-112

Known as: PT-112 
A platinum (Pt)-based agent belonging to the phosphaplatin family comprised of Pt complexed to a pyrophosphate ligand, with potential antineoplastic… 
National Institutes of Health

Papers overview

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2019
2019
Abstract B199: Potent induction of immunogenic cell death by PT-112
Purpose: To characterize the ability of PT-112 to induce immunogenic cell death (ICD) in vitro and in vivo. Background: PT-112 is… 
2017
2017
A phase I study of PT-112 in advanced solid tumors.
2519Background: PT-112 is a novel platinum-pyrophosphate agent designed to avoid the toxicity and drug resistance mechanisms of… 
2017
2017
Abstract 2378: A kinome analysis of the molecular pharmacodynamics of PT-112 in a human cancer cell line
2016
2016
Findings across pre-clinical models in the development of PT-112, a novel investigational platinum-pyrophosphate anti-cancer agent
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