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Phenoxybenzamine Hydrochloride

Known as: N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-benzenemethanamine Hydrochloride, Phenoxybenzamine Hydrochloride [Chemical/Ingredient], Hydrochloride, Phenoxybenzamine 
The hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory… 
National Institutes of Health

Related topics

Related topics

11 relations
Adrenergic alpha-Antagonists [MoA]Bladder neck obstructionDecreased Blood Pressure [PE]Hypersensitivity

Narrower (2)

DibenylineDibenzyline

Broader (1)

Phenoxybenzamine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Predictors of Hemodynamic Instability During Surgery for Pheochromocytoma
BackgroundResection of pheochromocytoma is often associated with hemodynamic instability (HDI). We examined patient and tumor… 
Review
1996
Review
1996
Chronic and Recurrent Muscle Pain
Objective: To review pharmacologic studies using needle electromyographically [EMG]-guided injection of trigger points [TrPs] in… 
Highly Cited
1995
Highly Cited
1995
Gonadotropin-releasing hormone (GnRH) pulse pattern regulates GnRH receptor gene expression: augmentation by estradiol.
GnRH acts via a single cell surface receptor (GnRH-R), and the number of pituitary GnRH-R increases on proestrus, after… 
1991
1991
Mechanism of hyperalgesia in SART stressed (repeated cold stress) mice: antinociceptive effect of neurotropin.
Exposing mice to 24 and 4 degrees C in alternate 1 hr periods in the day time and maintaining 4 degrees C at night for several… 
Highly Cited
1988
Highly Cited
1988
Activation of mesencephalic dopamine neurons by chemical stimulation of the nucleus tegmenti pedunculopontinus pars compacta
Highly Cited
1983
Highly Cited
1983
Rapid decrease in rat brain beta adrenergic receptor binding during combined antidepressant alpha-2 antagonist treatment.
The delay in onset of the therapeutic effect of antidepressants is believed to be due to a progressive decrease in the density of… 
1978
1978
N,N-Di-n-propyl dopamine: a qualitatively different dopamine vascular agonist.
N,N-di-n-propyl dopamine (DPDA) dilates the renal vascular bed by action on dopamine (DA) vascular receptors. In phenoxybenzamine… 
Highly Cited
1976
Highly Cited
1976
Possible involvement of a transmitter different from norepinephrine in the residual responses to nerve stimulation of the cat nictitating membrane after pretreatment with reserpine.
Pretreatment with reserpine (0.3 or 3 mg/kg, 24 hours before the experiment) reduced the norepinephrine (NE) levels in the medial… 
Highly Cited
1975
Highly Cited
1975
The diagnosis and treatment of Raynaud's phenomenon.
Twenty-five patients with Raynaud's phenomenon, including 20 with associated diseases and five with primary Raynaud's disease… 
Highly Cited
1971
Highly Cited
1971
Demonstration of Alpha and Beta Adrenergic Receptors in Canine Cerebral Vasculature
The cerebral vascular effects of various adrenomimetic agents were examined in 12 isolated canine brains perfused with blood at… 
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