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Phenformin

Known as: Imidodicarbonimidic diamide, N-(2-phenylethyl)-, Phenforminum, Fenformina 
A biguanide hypoglycemic agent with actions and uses similar to those of METFORMIN. Although it is generally considered to be associated with an… 
National Institutes of Health

Related topics

Related topics

14 relations

Narrower (3)

4-hydroxyphenforminphenethylguanidinetolbutaphen
HypoglycemiaIn BloodPhenformin Hydrochlorideagonists

Broader (2)

Hypoglycemic Agentsorganic nitrogen compounds

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Effect of treatment with combined phenformin and ethyloestrenol on the coagulation and fibrinolytic systems.
Administration of 100 mg phenformin combined with 8 mg ethyloestrenol for 30 days to 9 healthy volunteers raised the fibrinolytic… 
Highly Cited
2004
Highly Cited
2004
Molecularly imprinted solid-phase extraction for the screening of antihyperglycemic biguanides.
1973
1973
Mode of action of hypoglycemic agents. V. Studies with phenethylbiguanide in isolated perfused rat liver.
Abstract In isolated perfused rat liver, phenethylbiguanide inhibits the rate of glucose production from both lactate and… 
1970
1970
Lactate Turnover and Gluconeogenesis in Obesity: Effect of Phenformin
The effect of phenformin on the rates of lactate and glucose turnover, interconversion, and oxidation was determined in five… 
1965
1965
The action of substituted guanidines on mitochondrial respiration and on the ADP-ATP exchange reaction.
1964
1964
PHOSPHORYLATION COUPLED TO THE OXIDATION OF NADH BY FUMARATE IN DIGITONIN FRAGMENTS OF BEEF-HEART MITOCHONDRIA.
Highly Cited
1963
Highly Cited
1963
The Effects of Guanidine and Alkylguanidines on the Energy Transfer Reactions of Mitochondria
Considerable attention has been focused on the biological activity of guanidine derivatives from two main directions. Ever since… 
Review
1960
Review
1960
Tissue Distribution of C14-labeled Beta-phenethylbiguanide
Since the original report by Ungar et al. on the hypoglycemic action of phenethylbiguanide, now more commonly known as DBI, the… 
1959
1959
Secondary failure of response to tolbutamide treatment.
A group of 200 patients with diabetes mellitus were observed for periods of many months as to their response to continued… 
Highly Cited
1958
Highly Cited
1958
A site of action of phenethylbiguanide, a hypoglycemic compound.
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