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Perphenazine

Known as: Chlorpiprazine, Etaperazin, Perphénazine 
A phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties. Perphenazine blocks postsynaptic dopamine 2(D2… 
National Institutes of Health

Related topics

Related topics

38 relations
Adrenergic alpha-Antagonists [MoA]Amitriptyline / PerphenazineBlood Coagulation DisordersBone Marrow Diseases

Broader (5)

AntiemeticsAntipsychotic AgentsDopamine Antagonistsphenothiazine

Narrower (6)

EtrafonTrilafonTriptafenduo-tran

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study)
Highly Cited
2007
Highly Cited
2007
Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial.
CONTEXT Neurocognitive impairment in schizophrenia is severe and is an important predictor of functional outcome. The relative… 
Highly Cited
2006
Highly Cited
2006
Cost-effectiveness of second-generation antipsychotics and perphenazine in a randomized trial of treatment for chronic schizophrenia.
BACKGROUND Second-generation antipsychotics have largely replaced first-generation antipsychotics for the treatment of… 
Highly Cited
2006
Highly Cited
2006
Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach.
Highly Cited
2005
Highly Cited
2005
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia.
BACKGROUND The relative effectiveness of second-generation (atypical) antipsychotic drugs as compared with that of older agents… 
Highly Cited
2002
Highly Cited
2002
Comparison of citalopram, perphenazine, and placebo for the acute treatment of psychosis and behavioral disturbances in hospitalized, demented patients.
OBJECTIVE Until recently, conventional antipsychotics were the standard pharmacotherapy for psychosis and behavioral disturbances… 
Review
2000
Review
2000
Dexamethasone for the Prevention of Postoperative Nausea and Vomiting: A Quantitative Systematic Review
The role of dexamethasone in the prevention of postoperative nausea and vomiting (PONV) is unclear. We reviewed efficacy and… 
Highly Cited
1984
Highly Cited
1984
Pharmacological effects of a specific dopamine D-1 antagonist SCH 23390 in comparison with neuroleptics.
Highly Cited
1977
Highly Cited
1977
Behavioural stimulation induced by muscimol and other GABA agonists injected into the substantia nigra
Highly Cited
1970
Highly Cited
1970
Receptor activity and turnover of dopamine and noradrenaline after neuroleptics.
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