Penicillin-Binding Proteins

Known as: Penicillin Binding Proteins, Penicillin Binding Protein, Penicillin-Binding Proteins [Chemical/Ingredient] 
Bacterial proteins that share the property of binding irreversibly to PENICILLINS and other ANTIBACTERIAL AGENTS derived from LACTAMS. The penicillin… (More)
National Institutes of Health

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Narrower (19)

FtsI protein, E coliMrdA protein, E coliPBP 2x protein, StreptococcusPbpG protein, Bacillus subtilis
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In BloodMuramoylpentapeptide CarboxypeptidasePeptidyltransferaseProcess of secretion
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Papers overview

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Highly Cited
2010
Highly Cited
2010
Binding of ceftaroline to penicillin-binding proteins of Staphylococcus aureus and Streptococcus pneumoniae.
OBJECTIVES This study evaluated the affinity of ceftaroline and comparator beta-lactams for penicillin-binding proteins (PBPs) of… (More)
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Highly Cited
2005
Highly Cited
2005
Recruitment of penicillin-binding protein PBP2 to the division site of Staphylococcus aureus is dependent on its transpeptidation substrates.
Staphylococcus aureus penicillin-binding protein PBP2 is an enzyme involved in the last stages of peptidoglycan assembly and is… (More)
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Highly Cited
2004
Highly Cited
2004
The basis for resistance to beta-lactam antibiotics by penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus.
Penicillin-binding protein 2a (PBP2a) of Staphylococcus aureus is refractory to inhibition by available beta-lactam antibiotics… (More)
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2003
2003
Peptidoglycan synthesis in the absence of class A penicillin-binding proteins in Bacillus subtilis.
Penicillin-binding proteins (PBPs) catalyze the final, essential reactions of peptidoglycan synthesis. Three classes of PBPs… (More)
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Highly Cited
2002
Highly Cited
2002
Novel S-benzylisothiourea compound that induces spherical cells in Escherichia coli probably by acting on a rod-shape-determining protein(s) other than penicillin-binding protein 2.
Random screening for inhibitors of chromosome partitioning in Escherichia coli was done by the anucleate cell blue assay. A novel… (More)
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Highly Cited
1999
Highly Cited
1999
Escherichia coli mutants lacking all possible combinations of eight penicillin binding proteins: viability, characteristics, and implications for peptidoglycan synthesis.
The penicillin binding proteins (PBPs) synthesize and remodel peptidoglycan, the structural component of the bacterial cell wall… (More)
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Review
1999
Review
1999
beta-lactam resistance in Streptococcus pneumoniae: penicillin-binding proteins and non-penicillin-binding proteins.
The beta-lactams are by far the most widely used and efficacious of all antibiotics. Over the past few decades, however… (More)
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Review
1998
Review
1998
Resistant penicillin-binding proteins
Low-affinity penicillin-binding proteins (PBPs), which participate in the β-lactam resistance of several pathogenic bacteria… (More)
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Highly Cited
1975
Highly Cited
1975
Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12.
The varied effects of beta-lactam antibiotics on cell division, cell elongation, and cell shape in E. coli are shown to be due to… (More)
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Review
1974
Review
1974
Interaction of penicillin with the bacterial cell: penicillin-binding proteins and penicillin-sensitive enzymes.
INTRODUCTION ........................................................ 291 General… (More)
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