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Penicillin Amidase

Known as: Penicillin Acylase, Acylase, Penicillin, Penicillin amidohydrolase 
An enzyme catalyzing the hydrolysis of penicillin to penicin and a carboxylic acid anion. EC 3.5.1.11.
National Institutes of Health

Related topics

Related topics

12 relations
Cephalosporin AcylaseIn BloodProcess of secretionantagonists & inhibitors

Narrower (4)

Penicillin G AcylasePenicillin V Acylaseampicillin acylaseglutarylamidocephalosporanic acid acylase

Papers overview

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2014
2014
Erratum to: Penicillin G acylase from Achromobacter sp. CCM 4824
Penicillin G acylase from Achromobacter sp. (NPGA) was studied in the enzymatic synthesis of β-lactam antibiotics by kinetically… 
1986
1986
Direct evaluation of phenylacetyl-CoA: 6-aminopenicillanic acid acyltransferase of Penicillium chrysogenum by bioassay.
The enzyme phenylacetyl-CoA: 6-Aminopenicillanic acid acyltransferase of Penicillium chrysogenum was evaluated by direct bioassay… 
Highly Cited
1985
Highly Cited
1985
Enzymes in polyelectrolyte complexes. The effect of phase transition on thermal stability.
Penicillin amidase, alpha-chymotrypsin and urease have been immobilized in water-soluble nonstoichiometric polyelectrolyte… 
1984
1984
Kinetic studies on the mechanism of the penicillin amidase-catalysed synthesis of ampicillin and benzylpenicillin.
Hydrophobic protein chromatography was used to prepare homogeneous fractions of penicillin amidase (EC 3.5.1.11) from E. coli… 
1984
1984
Novel approaches to the purification of penicillin acylase
Penicillin acylase ofE. coli NCIM 2400 has been purified to homogeneity using a combination of hydrophobic interaction… 
1984
1984
Phenylalkylsulfonyl derivatives as covalent inhibitors of penicillin amidase.
It was demonstrated that phenylmethanesulfonyl fluoride-a very potent inhibitor of penicillin amidase from Escherichia coli-binds… 
1978
1978
Substrate specificity of penicillin acylase of E. coli.
The hydrolysis of several phenylacetylamino compounds was studied using a purified preparation of E. coli penicillin acylase. The… 
1976
1976
Continuous production of 6-aminopenicillanic acid from penicillin by immobilized microbial cells
SummaryFor continuous production of 6-aminopenicillanic acid (6-APA) the microbial cells ofEscherichia coli ATCC 9637 having high… 
1975
1975
Penicillinamidohydrolase in Escherichia coli. II. Synthesis of the enzyme, kinetics and specificity of its induction and the effect of O2.
The differential rate of synthesis of penicillinamidohydrolase (penicillin acylase -- EC 3.5.1.11) was studied in Escherichia… 
1968
1968
Specificity of penicillin acylase of Fusarium and of Penicillium chrysogenum.
Extracts containing penicillin acylase were obtained by shaking the mycelium of Fusarium avenaceum and of Penicillium chrysogenum… 
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