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Pargyline

Known as: Benzenemethanamine, N-methyl-N-2-propynyl-, N-Methyl-N-2-Propynylbenzylamine, Pargyline [Chemical/Ingredient] 
A monoamine oxidase (MAO) inhibitor with antidepressant activity. Pargyline selectively inhibits MAO type B, an enzyme catalyzing the oxidative… 
National Institutes of Health

Related topics

Related topics

29 relations

Narrower (17)

1-ethynyl-1-propargyl acetate2-iodopargyline3-phenylpropargylamine4-methoxy-benzoic acid propargylester

Broader (3)

Antihypertensive AgentsBenzylaminesMonoamine Oxidase Inhibitors
In BloodPargyline HydrochloridePargyline:MCnc:Pt:Ser/Plas:Qnagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1985
1985
Biodistribution of a positron-emitting suicide inactivator of monoamine oxidase, carbon-11 pargyline, in mice and a rabbit.
Carbon-11 (11C) pargyline, which is a suicide inactivator of Type B monoamine oxidase (MAO), was synthesized by the reaction of N… 
1985
1985
Bipolar affective symptoms associated with use of captopril and abrupt withdrawal of pargyline and propranolol.
A woman with a family history but no personal history of depression developed bipolar symptoms associated with manipulations of… 
1984
1984
Catecholamine-angiotensin II receptor interaction in primary cultures of rat brain.
Neuron-enriched primary cultures from 1-day-old rat brains have been used to study the influence of catecholamines on… 
Review
1983
Review
1983
Tricyclic antidepressants in the treatment of insomnia.
: The use of tricyclic antidepressants as opposed to hypnotics in treating insomnia is reviewed. Available data indicate that… 
1983
1983
Pargyline-induced mania in primary affective disorder: case report.
A case is described of a 47-year-old man who developed a manic psychosis while receiving pargyline treatment for concurrent… 
Review
1981
Review
1981
Monoamine oxidase inhibitor efficacy in depression and the ‘cheese effect’
It is widely agreed that the monoamine oxidase (MAO) inhibiting group of drugs have a useful role to play in the treatment of… 
Highly Cited
1978
Highly Cited
1978
2,5,5-Trimethylthiazolidine-4-carboxylic acid, a D(-)-penicillamine-directed pseudometabolite of ethanol. Detoxication mechanism for acetaldehyde.
A directed detoxication mechanism for acetaldehyde (AcH) is described wherein ethanol-derived AcH, circulating in the blood of… 
1978
1978
Inhibition of aldehyde dehydrogenase by propiolaldehyde, a possible metabolite of pargyline.
Pargyline (Eutonyl) inhibited aldehyde dehydrogenase (AlDH) in vivo in rats as adduced by the elevation of ethanol-derived blood… 
Highly Cited
1975
Highly Cited
1975
Tonic immobility in chickens: possible involvement of monoamines.
Tonic immobility in chickens was affected by a variety of drugs that act on monoaminergic systems. Compounds that enhanced the… 
1973
1973
Distribution and metabolism of tryptamine in rat brain.
Following intraventricular injection in untreated rats, the only metabolites of tryptamine isolated were indoleacetic acid and…