Pargyline

Known as: Benzenemethanamine, N-methyl-N-2-propynyl-, N-Methyl-N-2-Propynylbenzylamine, Pargyline [Chemical/Ingredient] 
A monoamine oxidase (MAO) inhibitor with antidepressant activity. Pargyline selectively inhibits MAO type B, an enzyme catalyzing the oxidative… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Lysine-specific demethylase 1 (LSD1) functions as a transcriptional coregulator by modulating histone methylation. Its role in… (More)
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Highly Cited
2006
Highly Cited
2006
Demethylation of histone H3 lysine 4 is carried out by BHC110/LSD1, an enzyme with close homology to monoamine oxidases (MAO… (More)
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Highly Cited
2005
Highly Cited
2005
Gene regulation in eukaryotes requires the coordinate interaction of chromatin-modulating proteins with specific transcription… (More)
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Highly Cited
2002
Highly Cited
2002
Monoamine oxidase B (MAO B) is a mitochondrial outermembrane flavoenzyme that is a well-known target for antidepressant and… (More)
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Highly Cited
1988
Highly Cited
1988
Mesolimbic dopaminergic neurons discharge either in a single spike mode or in a bursting pattern. In order to investigate the… (More)
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Highly Cited
1984
Highly Cited
1984
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin which produces permanent parkinsonism in human and nonhuman… (More)
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Highly Cited
1984
Highly Cited
1984
1-Methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) causes degeneration of the dopaminergic nigrostriatal pathway in several… (More)
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Highly Cited
1981
Highly Cited
1981
The initial activity of a rat placed in novel surroundings (i.e., open field activity) has been taken as an indicator of its… (More)
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1979
1979
The antidepressant and other behavioral effects of clorgyline, a preferential inhibitor of monoamine oxidase (MAO) type A, were… (More)
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Highly Cited
1976
Highly Cited
1976
Selective large scale destruction of mesolimbic dopamine-containing terminals is produced by bilateral injection of 8 mug of 6… (More)
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