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Par3-APC-KIF3A complex

Known as: Par3-APC-KIF3A complex location 
A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved… Expand
National Institutes of Health

Papers overview

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2019
2019
Acute Inhibition of Heterotrimeric Kinesin-2 Function Reveals Mechanisms of Intraflagellar Transport in Mammalian Cilia
The trafficking of components within cilia, called intraflagellar transport (IFT), is powered by kinesin-2 and dynein-2 motors… Expand
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2018
2018
Conditionally and acutely ablating Kif3a from oligodendrocyte progenitor cells impairs primary cilum assembly and cell function
The primary cilium is a cellular organelle that can regulate the behaviour of many mitotic progenitor cells, and even some post… Expand
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2015
2015
The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function
ABSTRACT GLI transport to the primary cilium and nucleus is required for proper Hedgehog (HH) signaling; however, the mechanisms… Expand
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Highly Cited
2013
Highly Cited
2013
NOTCH1–RBPJ complexes drive target gene expression through dynamic interactions with superenhancers
Significance Studies focused on understanding how transcription factors control gene expression have shown that transcription… Expand
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2011
2011
Identification of KIF3A as a Novel Candidate Gene for Childhood Asthma Using RNA Expression and Population Allelic Frequencies Differences
Background Asthma is a chronic inflammatory disease with a strong genetic predisposition. A major challenge for candidate gene… Expand
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2004
2004
The two motor domains of KIF3A/B coordinate for processive motility and move at different speeds.
KIF3A/B, a kinesin involved in intraflagellar transport and Golgi trafficking, is distinctive because it contains two… Expand
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