Pancreatic intraepithelial neoplasia

Known as: PanIN, Pancreatic Dysplasia 
A pre-cancerous, non-invasive pancreatic epithelial neoplasm that arises from and is confined to the pancreatic ducts. It is a papillary or flat… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
More information is needed about genetic factors that initiate development of pancreatic intraepithelial neoplasms-the most… (More)
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Highly Cited
2012
Highly Cited
2012
PURPOSE MicroRNA (miRNA) alterations are likely to contribute to the development of pancreatic cancer and may serve as markers… (More)
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Highly Cited
2011
Highly Cited
2011
Physiological levels of Kras(G12D) are sufficient to induce pancreatic intraepithelial neoplasias (PanINs); the mechanisms that… (More)
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Review
2011
Review
2011
Pancreatic intraepithelial neoplasias (PanINs) are microscopic lesions of the pancreas. Traditionally viewed as a benign… (More)
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Highly Cited
2008
Highly Cited
2008
Pancreatic intraepithelial neoplasia (PanIN) is a histologically well-defined precursor to invasive ductal adenocarcinoma of the… (More)
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Highly Cited
2007
Highly Cited
2007
A number of studies have shown that pancreatic ductal adenocarcinoma develops through precursor lesions termed pancreatic… (More)
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Review
2004
Review
2004
Invasive pancreatic ductal adenocarcinoma is an almost uniformly fatal disease. Several distinct noninvasive precursor lesions… (More)
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Highly Cited
2003
Highly Cited
2003
Hedgehog signalling—an essential pathway during embryonic pancreatic development, the misregulation of which has been implicated… (More)
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Highly Cited
2003
Highly Cited
2003
A multistep model for pancreatic adenocarcinoma has been proposed recently. In this model, well-defined, noninvasive ductal… (More)
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Highly Cited
2002
Highly Cited
2002
Pancreatic adenocarcinoma is believed to develop from histologically identifiable intraductal lesions known as pancreatic… (More)
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