Pancreatic carcinoma, familial

Known as: Familial Pancreatic Cancer, Familial Pancreatic carcinoma, Hereditary Pancreatic Cancer 
A carcinoma that arises from the pancreas in a patient with a family history of pancreatic cancer. In the minority of cases, patients have recognized… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
024619962018

Papers overview

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2011
2011
OBJECTIVES:Pancreatic adenocarcinoma is a lethal disease. Over 80% of patients are found to have metastatic disease at the time… (More)
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Highly Cited
2010
Highly Cited
2010
Recently, PALB2 was reported to be a new pancreatic cancer susceptibility gene as determined by exomic sequencing, as truncating… (More)
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2010
2010
Previous small scale studies reported that deleterious BRCA2 and CDKN2a germline mutations contribute to a subset of families… (More)
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2009
2009
PURPOSE: Histologic findings in 51 pancreata resected from patients with a strong family history of pancreatic cancer were… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVES:Approximately 10–15% of all pancreatic cancers (PCs) may be hereditary in origin. We investigated the use of… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE Familial pancreatic cancer (FPC) accounts for approximately 3% of all pancreatic cancer (PC) cases. It has been… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Pancreatic cancer is a deadly disease. Discovery of the mutated genes that cause the inherited form(s) of the disease… (More)
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2005
2005
Cystic fibrosis (CF) is a recessive disease caused by mutations of the CF transmembrane conductance regulator (CFTR) gene. The… (More)
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Highly Cited
2004
Highly Cited
2004
Individuals with a family history of pancreatic cancer have an increased risk of developing pancreatic cancer. Quantification of… (More)
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2002
2002
OBJECTIVE To evaluate the prevalence of mutations in the CDKN2A gene encoding p16 and p14 in familial pancreatic cancer (FPC… (More)
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