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Paired Mesoderm Homeobox Protein 2B

Known as: PHOX2B Homeodomain Protein, Paired-Like Homeobox 2B, Neuroblastoma Phox 
Paired mesoderm homeobox protein 2B (314 aa, ~32 kDa) is encoded by the human PHOX2B gene. This protein plays a role in the regulation of gene… 
National Institutes of Health

Related topics

Related topics

8 relations
DNA-Binding ProteinsGenes, RegulatorHomeodomain ProteinsPHOX2B gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Screening Children with a Family History of Central Congenital Hypoventilation Syndrome
Congenital central hypoventilation syndrome (CCHS) is a rare genetic disorder of an autonomic nervous disorder that affects… 
2019
2019
Analysis of the neuronal network of the medullary respiratory center in transgenic rats expressing archaerhodopsin-3 in Phox2b-expressing cells
2019
2019
A Novel c.676_677insG PHOX2B Mutation in Congenital Central Hypoventilation Syndrome.
ABSTRACT Paired-like homeobox (PHOX)2B is considered to be the causative gene of congenital central hypoventilation syndrome… 
Review
2014
Review
2014
Cytoarchitecture and CO(2) sensitivity of Phox2b-positive Parafacial neurons in the newborn rat medulla.
2013
2013
Several Cis-regulatory Elements Control mRNA Stability, Translation Efficiency, and Expression Pattern of Prrxl1 (Paired Related Homeobox Protein-like 1)*
Background: The mechanisms that control the Prrxl1 expression are poorly understood. Results: Several regulatory elements present… 
2011
2011
Spatial and temporal mechanisms of cell fate determination in the developing CNS
The generation of neural cell diversity in the developing central nervous system relies on mechanisms that provide spatial and… 
2007
2007
De novo polyalanine expansion of PHOX2B in congenital central hypoventilation syndrome: unequal sister chromatid exchange during paternal gametogenesis
AbstractThe expansion of polyalanine repeats is known to cause at least nine disorders, including congenital central… 
2004
2004
Haploinsufficiency for Phox 2 b in mice causes dilated pupils and atrophy of the ciliary ganglion : mechanistic insights into human congenital central hypoventilation syndrome
Dilp1 is a semi-dominant mouse mutation that causes dilated pupils when heterozygous and is lethal when homozygous. We report… 
Highly Cited
2000
Highly Cited
2000
Paired-like homeodomain proteins Phox2a/Arix and Phox2b/NBPhox have similar genetic organization and independently regulate dopamine beta-hydroxylase gene transcription.
The homeodomain transcription factors Arix/Phox2a and NBPhox/Phox2b play a role in the specification of the noradrenergic… 
1999
1999
Genomic structure and functional characterization of NBPhox (PMX2B), a homeodomain protein specific to catecholaminergic cells that is involved in second messenger-mediated transcriptional activation…
Homeodomain proteins play essential roles in basic processes during embryogenesis and development. NBPhox, a vertebrate paired… 
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