Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Paired Mesoderm Homeobox Protein 2B

Known as: PHOX2B Homeodomain Protein, Paired-Like Homeobox 2B, Neuroblastoma Phox 
Paired mesoderm homeobox protein 2B (314 aa, ~32 kDa) is encoded by the human PHOX2B gene. This protein plays a role in the regulation of gene… Expand
National Institutes of Health

Related topics

Related topics

8 relations
DNA-Binding ProteinsGenes, RegulatorHomeodomain ProteinsPHOX2B gene
Expand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways.
Taste and most sensory inputs required for the feedback regulation of digestive, respiratory, and cardiovascular organs are… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2008
Highly Cited
2008
CO2-sensitive preinspiratory neurons of the parafacial respiratory group express Phox2b in the neonatal rat.
Phox2b protein is a specific marker for neurons in the parafacial region of the ventral medulla, which are proposed to play a… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2008
2008
PHOX2B is a novel and specific marker for minimal residual disease testing in neuroblastoma.
PURPOSE Polymerase chain reaction (PCR)-based detection of minimal residual disease (MRD) in neuroblastoma can be used to monitor… Expand
  • table 1
  • figure 1
  • table 2
  • table 3
  • table 4
Is this relevant?
2005
2005
Phox2b function in the enteric nervous system is conserved in zebrafish and is sox10-dependent
Zebrafish lacking functional sox10 have defects in non-ectomesenchymal neural crest derivatives including the enteric nervous… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2005
2005
Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation.
The paralogous paired-like homeobox genes Phox2a and Phox2b are involved in the development of specific neural subtypes in the… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Distinct pathogenetic mechanisms for PHOX2B associated polyalanine expansions and frameshift mutations in congenital central hypoventilation syndrome.
Congenital central hypoventilation syndrome (CCHS) is a rare neurocristopathy characterized by absence of adequate autonomic… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
2004
2004
Integration of anteroposterior and dorsoventral regulation of Phox2b transcription in cranial motoneuron progenitors by homeodomain proteins.
Little is known about the molecular mechanisms that integrate anteroposterior (AP) and dorsoventral (DV) positional information… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Polyalanine expansion and frameshift mutations of the paired-like homeobox gene PHOX2B in congenital central hypoventilation syndrome
Congenital central hypoventilation syndrome (CCHS or Ondine's curse; OMIM 209880) is a life-threatening disorder involving an… Expand
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The Phox2b transcription factor coordinately regulates neuronal cell cycle exit and identity.
In the vertebrate neural tube, cell cycle exit of neuronal progenitors is accompanied by the expression of transcription factors… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis.
Recent evidence suggests that specific families of homeodomain transcription factors control the generation and survival of… Expand
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE