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PYGO2 gene

Known as: PYGO2, PYGOPUS, DROSOPHILA, HOMOLOG OF, 2, pygopus family PHD finger 2 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
miR‐516a‐3p inhibits breast cancer cell growth and EMT by blocking the Pygo2/Wnt signalling pathway
miR‐516a‐3p has been reported to play a suppressive role in several types of human tumours. However, the expression level… 
2018
2018
Pygo2 Regulates Adiposity and Glucose Homeostasis via β-Catenin–Axin2–GSK3β Signaling Pathway
Wnt/β-catenin signaling plays a key role in regulating adipogenesis through indirectly inhibiting the expression of C/EBPα and… 
Highly Cited
2017
Highly Cited
2017
Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9
Wnt/β-catenin signaling elicits context-dependent transcription switches that determine normal development and oncogenesis. These… 
Highly Cited
2016
Highly Cited
2016
Pygo2 activates MDR1 expression and mediates chemoresistance in breast cancer via the Wnt/β-catenin pathway
The Wnt/β-catenin pathway has important roles in chemoresistance and multidrug resistance 1 (MDR1) expression in some cancers… 
Review
2016
Review
2016
Long Non-coding RNAs in Urologic Malignancies: Functional Roles and Clinical Translation
Early diagnosis and surveillance for metastasis and recurrences are critical issues of urologic cancer. Deregulation of long non… 
2016
2016
Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment
Pygo2 has been discovered as an important Wnt signaling component contributing to the activation of Wnt-target gene transcription… 
2010
2010
Allosteric Remodelling of the Histone H3 Binding Pocket in the Pygo2 PHD Finger Triggered by Its Binding to the B9L/BCL9 Co-Factor
2010
2010
Mandibulofacial dysostosis, microtia, and limb anomalies in a newborn: a new form of acrofacial dysostosis syndrome?
Zhang Y, Dai Y, Liu Y, Ren J. Mandibulofacial dysostosis, microtia, and limb anomalies in a newborn: a new form of acrofacial… 
Highly Cited
2008
Highly Cited
2008
Gene expression profiling in hepatocellular carcinoma: upregulation of genes in amplified chromosome regions
Cytogenetics of hepatocellular carcinoma and adenoma have revealed gains of chromosome 1q as a significant differentiating factor… 
Highly Cited
2007
Highly Cited
2007
pygopus 2 has a crucial, Wnt pathway-independent function in lens induction
Drosophila Pygopus was originally identified as a core component of the canonical Wnt signaling pathway and a transcriptional… 
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