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PYGO2 gene

Known as: PYGO2, PYGOPUS, DROSOPHILA, HOMOLOG OF, 2, pygopus family PHD finger 2 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
An Screen Identifies PYGO2 as a Driver for Metastatic Prostate Cancer.
2017
2017
Diallyl trisulfide inhibits proliferation, invasion and angiogenesis of glioma cells by inactivating Wnt/β-catenin signaling
Aberrant activation of Wnt/β-catenin signaling leads to increased cell proliferation and survival and promotes the development of… 
2016
2016
Downregulation of Pygopus 2 inhibits vascular mimicry in glioma U251 cells by suppressing the canonical Wnt signaling pathway.
Gliomas are the most common type of malignant primary brain tumor, and the Wnt signaling pathway is associated with glioma… 
2016
2016
Unexpected survival of mice carrying a mutation in Pygo2 that strongly reduces its binding to Bcl9/9l
Pygopus is a transcriptional activator important for the Wnt signaling pathway. It binds to the beta-catenin transcriptional… 
2016
2016
Correlation of Wnt and NOTCH pathways in esophageal squamous cell carcinoma
There is an inevitable association between cell signaling pathways and tumorigenesis. Wnt and notch pathways play important roles… 
2016
2016
The role of Pygo2 during intestinal tumor initiation and progression in vivo
Canonical Wnt signaling pathway is an essential regulator of embryonic development as well homeostasis of adult tissues and stem… 
2015
2015
Pygo2 siRNA Inhibit the Growth and Increase Apoptosis of U251 Cell by Suppressing Histone H3K4 Trimethylation
The development of novel therapeutic strategies for glioma requires the identification of molecular targets involved in… 
2015
2015
Role of Msi1 and PYGO2 in esophageal squamous cell carcinoma depth of invasion
Deregulation of developmental signaling pathways such as Wnt/b-catenin and NOTCH are commonly observed in different cancers. A… 
2013
2013
[Association of single nucleotide polymorphisms(SNPs) in Pygo2 coding gene with idiopathic oligospermia and azoospermia].
Male infertility is often associated with a decreased sperm count. Pygo2 gene is expressed in the elongating spermatid when… 
2009
2009
Overexpression of Pygopus2 protects HeLa cells from vinblastine-induced apoptosis
Abstract Pygopus, a very important component of the Wnt signaling transcriptional complex, has multiple functions in both Wnt… 
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