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PURA wt Allele

Known as: PUR1, PURALPHA, PUR-Alpha 
Human PURA wild-type allele is located within 5q31 and is approximately 3 kb in length. This allele, which encodes transcriptional activator protein… 
National Institutes of Health

Related topics

Related topics

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DNA ReplicationLeukemia, Myelocytic, AcuteMYELODYSPLASTIC SYNDROMEPurA protein

Broader (1)

PURA gene

Papers overview

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Highly Cited
2015
Highly Cited
2015
De novo mutations in PURA are associated with hypotonia and developmental delay
PURA is the leading candidate gene responsible for the developmental phenotype in the 5q31.3 microdeletion syndrome. De novo… 
Highly Cited
2015
Highly Cited
2015
Knowledge regarding antenatal care services, its utilization, and delivery practices in mothers (aged 15-49 years) in a rural area of North India
Background: Antenatal care (ANC) is an effective tool to reduce both infant and maternal mortality rates. In spite of all efforts… 
Review
2009
Review
2009
Multiple roles for Pur-α in cellular and viral regulation
Pur-alpha is a ubiquitous multifunctional protein that is strongly conserved throughout evolution, binds to both DNA and RNA and… 
Highly Cited
2001
Highly Cited
2001
Ras‐induced colony formation and anchorage‐independent growth inhibited by elevated expression of Purα in NIH3T3 cells
Levels of Purα, a conserved, sequence‐specific single‐stranded DNA and RNA binding protein, fluctuate during the cell cycle… 
Highly Cited
2000
Highly Cited
2000
Regulation of the human fas promoter by YB-1, Puralpha and AP-1 transcription factors.
2000
2000
Interaction of HIV‐1 Tat with Purα in nuclei of human glial cells: Characterization of RNA‐mediated protein‐protein binding
A complex between the Tat protein, encoded by human immunodeficiency virus type 1 (HIV‐1), and the cellular protein, Purα, has… 
Highly Cited
1999
Highly Cited
1999
Reciprocal Interaction between Two Cellular Proteins, Purα and YB-1, Modulates Transcriptional Activity of JCVCY in Glial Cells
ABSTRACT Cross communication between regulatory proteins is an important event in the control of eukaryotic gene transcription… 
Highly Cited
1998
Highly Cited
1998
Interaction of the Single-stranded DNA-binding Protein Purα with the Human Polyomavirus JC Virus Early Protein T-antigen*
Large T-antigen, the major regulatory protein encoded by polyomaviruses, including Simian Virus 40 (SV40) and JC virus (JCV), is… 
1998
1998
Association of Purα with RNAs Homologous to 7 SL Determines Its Binding Ability to the Myelin Basic Protein Promoter DNA Sequence*
Cell type and developmental stage expression of the myelin basic protein (MBP) gene in mouse brain is regulated at the… 
Highly Cited
1997
Highly Cited
1997
Transcriptional Regulation of Neuronal Nicotinic Acetylcholine Receptor Genes
Nicotinic acetylcholine receptors constitute a multigene family (α2–α9, β2–β4) expressed in discrete temporal and spatial… 
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