PurA protein

Known as: Transcriptional Activator Protein Pur-Alpha, PURA, Transcription Factor PUR1 
Transcriptional activator protein Pur-alpha (322 aa, ~35 kDa) is encoded by the human PURA gene. This protein is involved in the modulation of DNA… (More)

Topic mentions per year

Topic mentions per year

1995-2018
02419952018

Papers overview

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Review
2018
Review
2018
The PURA gene encodes Pur-alpha, a 322 amino acid protein with repeated nucleic acid binding domains that are highly conserved… (More)
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2015
2015
PURA is the leading candidate gene responsible for the developmental phenotype in the 5q31.3 microdeletion syndrome. De novo… (More)
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2014
2014
5q31.3 microdeletion syndrome is characterized by neonatal hypotonia, encephalopathy with or without epilepsy, and severe… (More)
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2013
2013
In order to improve the anticancer effect of drug, we designed and prepared biodegradable nanogel based on all-trans retinoic… (More)
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2012
2012
The ERBB2 gene (HER2/neu) is overexpressed in many human breast cancers. It is an important therapeutic target and its product… (More)
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2010
2010
Purα is an evolutionarily conserved cellular protein participating in processes of DNA replication, transcription, and RNA… (More)
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2008
2008
BACKGROUND The nucleic acid-binding protein Puralpha is involved at stalled DNA replication forks, in double-strand break (DSB… (More)
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2006
2006
Using genetic inactivation in the mouse, PURA, encoding Pur alpha, is demonstrated to be essential for developmentally-timed… (More)
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2001
2001
Deletions or monosomy of chromosomes 5 and 7 are frequently observed in myelodysplastic syndromes (MDS) and acute myelogenous… (More)
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1995
1995
Pur alpha (PurA) is a sequence-specific single-stranded-DNA-binding protein implicated in control of both DNA replication and… (More)
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