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PTX3 wt Allele

Known as: Tumor Necrosis Factor, Alpha-Induced Protein 5 Gene, Tumor Necrosis Factor-Inducible Gene 14, TSG-14 
Human PTX3 wild-type allele is located in the vicinity of 3q25 and is approximately 7 kb in length. This allele, which encodes pentraxin-related… Expand
National Institutes of Health

Related topics

Related topics

3 relations
Ligand BindingPhagocytosis Inductioninflammatory response

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Tumor Necrosis Factor Alpha-Induced Proteins in Malignant Tumors: Progress and Prospects
Abstract Tumor necrosis factor (TNF) is the first cytokine used in tumor biotherapy, but TNF-related drugs are limited by the… Expand
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2012
2012
CCAAT/enhancer binding protein delta (CEBPD) elevating PTX3 expression inhibits macrophage-mediated phagocytosis of dying neuron cells
The CCAAT/enhancer binding protein delta (CEBPD, C/EBPδ, NF-IL6β) is induced in many inflammation-related diseases, suggesting… Expand
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2011
2011
Pentraxin 3 as a Novel Marker in Cardiovascular Diseases?
Pentraxin 3 (also known as TNFAIP5, TSG-14) belongs to the superfamily of proteins characterized by cyclic multimeric structure… Expand
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Highly Cited
2003
Highly Cited
2003
Characterization of the long pentraxin PTX3 as a TNFalpha-induced secreted protein of adipose cells.
Exposure of preadipocytes to long-chain fatty acids induces the expression of several markers of adipocyte differentiation. In an… Expand
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Highly Cited
2002
Highly Cited
2002
Increased mortality and inflammation in tumor necrosis factor-stimulated gene-14 transgenic mice after ischemia and reperfusion injury.
TSG-14/PTX3 is a gene inducible by tumor necrosis factor (TNF)-alpha, interleukin-1 beta, and lipopolysaccharide in fibroblasts… Expand
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Highly Cited
1993
Highly Cited
1993
TSG-14, a tumor necrosis factor- and IL-1-inducible protein, is a novel member of the pentaxin family of acute phase proteins.
TNF-stimulated gene (TSG)-14 was originally identified as a TNF-inducible gene in a differentially screened cDNA library derived… Expand
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