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PTPRS protein, human

Known as: Protein Tyrosine Phosphatase PTPsigma, Receptor-Type Tyrosine-Protein Phosphatase S, PTPRS 
Receptor-type tyrosine-protein phosphatase S (1948 aa, ~217 kDa) is encoded by the human PTPRS gene. This protein is involved in the… 
National Institutes of Health

Related topics

Related topics

30 relations
CDC25C protein, humanDUSP1 protein, humanDUSP3 protein, humanDUSP5 protein, human

Broader (1)

Receptor-Like Protein Tyrosine Phosphatases, Class 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
PTPRS drives adaptive resistance to MEK/ERK inhibitors through SRC
PTPRS is the most commonly mutated receptor tyrosine phosphatase in colorectal cancer (CRC). PTPRS has been shown to directly… 
2018
2018
PTPRS and PER3 methylation levels are associated with childhood obesity: results from a genome‐wide methylation analysis
The global prevalence of childhood overweight and obesity has increased in the last years. Epigenetic dysregulation affecting… 
2018
2018
PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation
Colorectal cancer (CRC) growth and progression is frequently driven by RAS pathway activation through upstream growth factor… 
2015
2015
Protein tyrosine phosphatase receptor S acts as a metastatic suppressor in hepatocellular carcinoma by control of epithermal growth factor receptor–induced epithelial‐mesenchymal transition
Hepatocellular carcinoma (HCC) is the third‐most lethal cancer worldwide. Understanding the molecular pathogenesis of HCC… 
Highly Cited
2013
Highly Cited
2013
Infarct-Derived Chondroitin Sulfate Proteoglycans Prevent Sympathetic Reinnervation after Cardiac Ischemia-Reperfusion Injury
Sympathetic nerves can regenerate after injury to reinnervate target tissues. Sympathetic regeneration is well documented after… 
Highly Cited
2009
Highly Cited
2009
Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases.
Congenital anomalies affecting the ureter-bladder junction are frequent in newborns and are often associated with other… 
Review
2008
Review
2008
Apical junction complex proteins and ulcerative colitis: a focus on the PTPRS gene
Inflammatory bowel disease is a complex multifactorial disease with a strong genetic component. Recent studies have identified… 
Highly Cited
2007
Highly Cited
2007
Protein-Tyrosine Phosphatase Sigma Is Associated with Ulcerative Colitis
Highly Cited
1999
Highly Cited
1999
Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase σ
Protein tyrosine phosphatase σ (PTP-σ, encoded by the Ptprs gene) is a member of the LAR subfamily of receptor-like protein… 
1996
1996
Physical mapping of receptor type protein tyrosine phosphatase sigma (PTPRS) to human chromosome 19p13.3.
Receptor type protein tyrosine phosphatase sigma (PTPRS), a member of a subfamily of receptor type protein tyrosine phosphatases… 
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