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PTPRQ gene

Known as: PTPGMC1, protein tyrosine phosphatase, receptor type Q, PROTEIN-TYROSINE PHOSPHATASE, RECEPTOR-TYPE, EXPRESSED BY GLOMERULAR MESANGIAL CELLS 1 
National Institutes of Health

Related topics

Related topics

2 relations
PTPRR wt AllelePTPRS gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
First confirmatory study on PTPRQ as an autosomal dominant non-syndromic hearing loss gene
Biallelic PTPRQ pathogenic variants have been previously reported as causative for autosomal recessive non-syndromic hearing loss… 
2017
2017
The Tetraspanin-Associated Uroplakins Family (UPK2/3) Is Evolutionarily Related to PTPRQ, a Phosphotyrosine Phosphatase Receptor
Uroplakins are a widespread group of vertebrate integral membrane proteins that belong to two different families: UPK1a and UPK1b… 
2016
2016
High PTPRQ Expression and Its Relationship to Expression of PTPRZ1 and the Presence of KRAS Mutations in Colorectal Cancer Tissues.
BACKGROUND The risk of sporadic colorectal cancer (CRC) is strongly influenced by Iifestyle, environmental and genetic factors… 
2015
2015
Identification of a novel compound heterozygous mutation in PTPRQ in a DFNB84 family with prelingual sensorineural hearing impairment
With a prevalence of 0.1 %, hearing loss is among the most common sensory impairments and affects several million people around… 
2013
2013
Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates.
Unlike other classical protein tyrosine phosphatases (PTPs), PTPRQ (PTP receptor type Q) has dephosphorylating activity towards… 
2013
2013
Identification of novel PTPRQ phosphatase inhibitors based on the virtual screening with docking simulations
Protein tyrosine phosphatase receptor type Q (PTPRQ) is an unusual PTP that has intrinsic dephosphorylating activity for various… 
Highly Cited
2010
Highly Cited
2010
Mutations in PTPRQ are a cause of autosomal-recessive nonsyndromic hearing impairment DFNB84 and associated with vestibular dysfunction.
Highly Cited
2003
Highly Cited
2003
Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation
Protein tyrosine phosphatase RQ (PTPRQ) was initially identified as a protein tyrosine phosphatase (PTPase)-like protein that is… 
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