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PTPN12 protein, human

Known as: PTPN12, protein tyrosine phosphatase, non-receptor type 12, human, Protein Tyrosine Phosphatase, Non-Receptor Type 12 
Tyrosine-protein phosphatase non-receptor type 12 (780 aa, ~88 kDa) is encoded by the human PTPN12 gene. This protein plays a role in both… Expand
National Institutes of Health

Papers overview

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2015
2015
PTPN12 is a cytoplasmic protein tyrosine phosphatase (PTP) reported to be a tumor suppressor in breast cancer, through its… Expand
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2015
2015
AIMS The present study showed that the expression of PTPN12 is epigenetically regulated. 5-Azacytidine (5-Azac), a DNA… Expand
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2014
2014
Dendritic cells (DCs) capture and process antigens in peripheral tissues, migrate to lymphoid tissues, and present the antigens… Expand
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2014
2014
It is well known that protein tyrosine phosphatases (PTPs) that become oxidized due to exposure to reactive oxygen species (ROS… Expand
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2014
2014
BACKGROUND Protein tyrosine phosphatase non-receptor type 12 (PTPN12), has been identified as a potent tumor suppressor in human… Expand
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Highly Cited
2013
Highly Cited
2013
Cell-surface receptors frequently use scaffold proteins to recruit cytoplasmic targets, but the rationale for this is uncertain… Expand
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2013
2013
Protein tyrosine phosphatase nonreceptor type 12 (PTPN12) has been recognized as a tumor suppressor gene that may inhibit tumor… Expand
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2012
2012
Protein-tyrosine phosphatase (PTP)-PEST (PTPN12) is ubiquitously expressed. It is essential for normal embryonic development and… Expand
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Highly Cited
2011
Highly Cited
2011
Among breast cancers, triple-negative breast cancer (TNBC) is the most poorly understood and is refractory to current targeted… Expand
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2011
2011
BACKGROUND HER2 activation in tumours supports multiple signalling pathways, including those regulating invasion and metastasis… Expand
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