PTPN12 protein, human

Known as: PTPN12, protein tyrosine phosphatase, non-receptor type 12, human, Protein Tyrosine Phosphatase, Non-Receptor Type 12 
Tyrosine-protein phosphatase non-receptor type 12 (780 aa, ~88 kDa) is encoded by the human PTPN12 gene. This protein plays a role in both… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
0246819922017

Papers overview

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2015
2015
PTPN12 is a cytoplasmic protein tyrosine phosphatase (PTP) reported to be a tumor suppressor in breast cancer, through its… (More)
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2014
2014
BACKGROUND Protein tyrosine phosphatase non-receptor type 12 (PTPN12), has been identified as a potent tumor suppressor in human… (More)
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2014
2014
It is well known that protein tyrosine phosphatases (PTPs) that become oxidized due to exposure to reactive oxygen species (ROS… (More)
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2013
2013
BACKGROUND Low tyrosine-protein phosphatase nonreceptor type 12 (PTPN12) expression may be associated with breast cancer growth… (More)
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2012
2012
Several tyrosine phosphatases control cell motility; understanding their signaling helps to decipher cancer mechanisms… (More)
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Highly Cited
2011
Highly Cited
2011
Among breast cancers, triple-negative breast cancer (TNBC) is the most poorly understood and is refractory to current targeted… (More)
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2011
2011
BACKGROUND HER2 activation in tumours supports multiple signalling pathways, including those regulating invasion and metastasis… (More)
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2007
2007
The protein tyrosine phosphatase PEST (PTP-PEST) is involved in the regulation of the actin cytoskeleton. Despite the emerging… (More)
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2007
2007
OBJECTIVE Protein tyrosine phosphatases (PTPs), such as PTPN22, are important regulators of signal transduction from the T cell… (More)
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1992
1992
We have cloned and characterized a human cDNA encoding a new member of the family of cytosolic type protein-tyrosine-phosphatase… (More)
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