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PTP4A3 gene

Known as: PRL-3, PRL-R, PROTEIN-TYROSINE PHOSPHATASE, TYPE 4A, 3 
 
National Institutes of Health

Papers overview

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Review
2010
Review
2010
The deregulated expression of members of the phosphatase of regenerating liver (PRL) family has been implicated in the metastatic… Expand
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Highly Cited
2008
Highly Cited
2008
The p53 tumor suppressor restricts tumorigenesis through the transcriptional activation of target genes involved in cell-cycle… Expand
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Highly Cited
2007
Highly Cited
2007
PRL-3 is a metastasis-associated phosphatase. We and others have shown that its overexpression increases cell motility and… Expand
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Highly Cited
2006
Highly Cited
2006
A series of rhodanine derivatives was synthesized and evaluated for their ability to inhibit PRL-3. Benzylidene rhodanine… Expand
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Highly Cited
2006
Highly Cited
2006
Protein tyrosine phosphatase PRL-3 mRNA was found highly expressed in colon cancer endothelium and metastases. We sought to… Expand
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Highly Cited
2006
Highly Cited
2006
PRL-3 is a newly identified protein tyrosine phosphatase associated with tumor metastasis. It is over-expressed in various… Expand
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Highly Cited
2005
Highly Cited
2005
Purpose: The PRL-3 phosphatase has been found expressed at higher levels in metastasis than in primary tumors of patients with… Expand
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Highly Cited
2004
Highly Cited
2004
  • X. Wu, H. Zeng, +6 authors Q. Xu
  • The American journal of pathology
  • 2004
  • Corpus ID: 29181564
Recent reports suggested that phosphatase of regenerating liver (PRL)-3 might be involved in colorectal carcinoma metastasis with… Expand
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Highly Cited
2004
Highly Cited
2004
Phosphatases and kinases are the cellular signal transduction enzymes that control protein phosphorylation. PRL phosphatases… Expand
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Highly Cited
2003
Highly Cited
2003
PURPOSE Expression of the PRL-3 tyrosine phosphatase is elevated in liver metastases derived from colorectal cancer (CRC). We… Expand
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