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PTHLH wt Allele

Known as: BDE2, Osteostatin Gene, PTHRP 
Human PTHLH wild-type allele is located within 12p12.1-p11.2 and is approximately 14 kb in length. This allele, which encodes parathyroid hormone… 
National Institutes of Health

Related topics

Related topics

10 relations
12p12.1-p11.2Cell ProliferationCell Proliferation Regulatory ProcessHomo sapiens

Broader (1)

PTHLH gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Site-directed mutagenesis on human cystathionine-gamma-lyase reveals insights into the modulation of H2S production.
Highly Cited
2007
Highly Cited
2007
The PTHrP–Ihh Feedback Loop in the Embryonic Growth Plate Allows PTHrP to Control Hypertrophy and Ihh to Regulate Proliferation
Growth plate and long bone development is governed by biochemical signaling pathways of which the PTHrP–Ihh system is the best… 
2004
2004
Temporal Changes in PTHrP, Bcl-2, Bax, Caspase, TGF-β, and FGF-2 Expression Following Growth Plate Irradiation With or Without Radioprotectant
This study examined temporal changes in growth plate apoptosis molecules and growth factors in an animal model of radiation… 
2003
2003
Perspective: PTH/PTHrP Activity and the Programming of Skeletal Development In Utero
There is increasing evidence that nutritional deficiency in utero adversely affects bone development and the risk of developing… 
2002
2002
Both N- and C-terminal Domains of Parathyroid Hormone-related Protein Increase Interleukin-6 by Nuclear Factor-κB Activation in Osteoblastic Cells*
Parathyroid hormone (PTH)-related protein (PTHrP) seems to affect bone resorption by interaction with bone cytokines, among them… 
Review
2001
Review
2001
Hypercalcemia of malignancy--new insights into an old syndrome.
Hypercalcemia is a common paraneoplastic syndrome. Tumors induce hypercalcemia by a local mechanism associated with the tumor's… 
Highly Cited
1997
Highly Cited
1997
PTHrP and cell division: Expression and localization of PTHrP in a keratinocyte cell line (HaCaT) during the cell cycle
Parathyroid hormone‐related protein (PTHrP) is highly expressed in normal skin keratinocytes, and its involvement in growth and… 
1997
1997
Clonal heterogeneity of the growth and invasive response of a human breast carcinoma cell line to parathyroid hormone-related peptide fragments.
It has been previously reported that 8701-BC cells, derived from a primary carcinoma of the breast, constitutively express… 
Highly Cited
1994
Highly Cited
1994
Intracellular transport and sorting of the oligodendrocyte transmembrane proteolipid protein
Delineating the properties and functions of the major central nervous system myelin proteins has been the focus of intensive… 
Highly Cited
1962
Highly Cited
1962
The site of binding of pyridoxal-5'-phosphate to heart glutamic-aspartic transaminase.
Pyridoxal-5'-phosphate (PLP) plays a central role as a cofactor of many enzymes of amino acid metabolism. In addition, the… 
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