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Vascular endothelial growth factor receptors in osteoclast differentiation and function.

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Expression of an N-methyl-D-aspartate-type receptor by human and rat osteoblasts and osteoclasts suggests a novel glutamate signaling pathway in bone.

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Microcellular polyHIPE polymer supports osteoblast growth and bone formation in vitro.

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The enhancement of osteoblast growth and differentiation in vitro on a peptide hydrogel-polyHIPE polymer hybrid material.

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Vascular endothelial growth factor acts as an osteolytic factor in breast cancer metastases to bone

It is shown that VEGF in the presence of RANKL supports PBMC differentiation into osteoclast-like cells, able to resorb substrate, and may play a role in physiological bone resorption and in pathological situations.
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Parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor expression and mitogenic responses in human breast cancer cell lines.

The expression of PTH/PTHRP receptor by breast cancer cells suggests that PTHrP may be a paracrine/autocrine regulator of breast carcinoma.
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Identification and cloning of human P2U purinoceptor present in osteoclastoma, bone, and osteoblasts

The cloned and sequenced the P2U purinoceptor from osteoclastoma is confirmed, and data suggest that purinergic agonists may play a role in the regulation of bone metabolism.
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Expression and secretion of parathyroid hormone‐related protein by human bone‐derived cells in vitro: Effects of glucocorticoids

Production of parathyroid hormone‐related protein was inhibited by 10−6 M of the glucocorticoids, prednisolone and desacetylated deflazacort, in a dose‐dependent manner, and Transcripts for PTHrP were detected in a purified population of alkaline phosphatase positive cells isolated from human bone marrow cultures by flow cytometry, confirming the expression of P THrP mRNA by cells of the osteoblastic lineage.
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Absence of paramyxovirus RNA in cultures of pagetic bone cells and in pagetic bon

The work presented here further questions the role of measles and CDV in the abnormal remodeling observed in Paget's disease.
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Zic1 transcription factor in bone: neural developmental protein regulates mechanotransduction in osteocytes

It is concluded that Zicl, a neural developmental transcription factor, plays an important role in shear flow mechanotransduction in osteocytes and may act as a link between mechanosensing and Wnt signaling.
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