Skip to search formSkip to main contentSkip to account menu

PTCH1 wt Allele

Known as: BCNS, PTCH, Patched (Drosophila) Homolog Gene 
Human PTCH1 wild-type allele is located in the vicinity of 9q22.3 and is approximately 65 kb in length. This allele, which encodes protein patched… 
National Institutes of Health

Related topics

Related topics

15 relations
9q22.3Axon GuidanceBasal Cell Nevus SyndromeBasal cell carcinoma

Broader (1)

PTCH gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Beta-catenin and survivin expression in keratocystic odontogenic tumor (KCOT). A comparative immunohistochemical study in primary, recurrent and nevoid basal cell carcinoma syndrome (NBCCS…
AIM To determine the epithelial expression of β-catenin and survivin in sporadic (primary, and recurrent) and nevoid basal cell… 
2013
2013
Molecular pathogenesis of keratocystic odontogenic tumors developing in nevoid basal cell carcinoma syndrome.
2010
2010
Activation of the Hedgehog pathway in pilocytic astrocytomas
Pilocytic astrocytoma is commonly viewed as a benign lesion. However, disease onset is most prevalent in the first two decades of… 
2008
2008
Ultraviolet responses of Gorlin syndrome primary skin cells
Background  Gorlin syndrome, or naevoid basal cell carcinoma syndrome (NBCCS), is an autosomal dominant disorder associated with… 
2008
2008
Cell proliferation and apoptosis in keratocystic odontogenic tumors.
OBJECTIVES Keratocystic odontogenic tumors (KOTs), also known as odontogenic keratocysts, were recently classified as a benign… 
2005
2005
Down-regulation of SMT3A gene expression in association with DNA synthesis induction after X-ray irradiation in nevoid basal cell carcinoma syndrome (NBCCS) cells.
2004
2004
Functional analysis in Drosophila indicates that the NBCCS/PTCH1 mutation G509V results in activation of smoothened through a dominant‐negative mechanism
Mutations in the human homolog of the patched gene are associated with the developmental (and cancer predisposition) condition… 
2003
2003
Molecular approaches to the diagnosis of sporadic and nevoid basal cell carcinoma syndrome-associated odontogenic keratocysts.
Review
1999
Review
1999
Mechanisms of mutagenesis in mammalian cells. Application to human thyroid tumours.
1995
1995
The human growth-arrest-specific gene GAS1 maps outside the candidate region of the gene for nevoid basal cell carcinoma syndrome.
The human growth-arrest specific gene GAS1 maps to chromosome bands 9q21.3-->q22, the region known to contain the tumour… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)