PTCH1 wt Allele

Known as: BCNS, PTCH, Patched (Drosophila) Homolog Gene 
Human PTCH1 wild-type allele is located in the vicinity of 9q22.3 and is approximately 65 kb in length. This allele, which encodes protein patched… (More)
National Institutes of Health

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Topic mentions per year

1983-2017
051019832017

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2012
2012
Nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder characterized by developmental defects and… (More)
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2008
2008
BACKGROUND Naevoid basal cell carcinoma syndrome (NBCCS) is a pleiotropic, autosomal dominant disease. Growing evidence suggests… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To investigate the frequency, type and distribution of PTCH mutations in odontogenic keratocysts (OKC) and to analyze… (More)
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Highly Cited
2006
Highly Cited
2006
The naevoid basal cell carcinoma syndrome (NBCCS) is caused by mutations in the hedgehog receptor PTCH gene. It is characterized… (More)
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Highly Cited
2000
Highly Cited
2000
The PTCH gene encodes a putative tumor suppressor protein; germline alterations in PTCH have been found in patients with the… (More)
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Highly Cited
1997
Highly Cited
1997
Nevoid basal cell carcinoma syndrome (NBCCS), or Gorlin's syndrome, is an autosomal dominant disorder that predisposes to… (More)
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Highly Cited
1997
Highly Cited
1997
The human homologue of the Drosophila segment polarity gene patched is implicated in the development of nevoid basal cell… (More)
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Highly Cited
1996
Highly Cited
1996
The nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder characterized by multiple basal cell… (More)
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Highly Cited
1996
Highly Cited
1996
The nevoid basal cell carcinoma (Gorlin) syndrome (NBCCS) is an autosomal dominant disorder characterized by multiple… (More)
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1995
1995
Patients with the nevoid basal cell carcinoma syndrome (NBCCS) are at increased risk for medulloblastomas as well as for basal… (More)
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