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PTBP3 gene

Known as: PTBP3, Polypyrimidine Tract Binding Protein 3 Gene, polypyrimidine tract binding protein 3 
This gene plays a role in RNA splicing, cellular differentiation and erythropoiesis.
National Institutes of Health

Related topics

Related topics

4 relations
ErythropoiesisPolypyrimidine Tract-Binding Protein 3RNA BindingRNA Splicing

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
LncRNA BCRT1 promotes breast cancer progression by targeting miR-1303/PTBP3 axis
Long noncoding RNAs (lncRNAs) play crucial roles in tumor progression and are aberrantly expressed in various cancers. However… 
2020
2020
WGCNA Co-Expression Network Analysis Reveals ILF3-AS1 Functions as a CeRNA to Regulate PTBP1 Expression by Sponging miR-29a in Gastric Cancer
Gastric cancer (GC) is one of the most common types of human cancers worldwide. However, the detail mechanisms underlying GC… 
2019
2019
PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α
Colorectal cancer (CRC) remains the fourth most common cause of cancer-related mortality worldwide. We aimed to identify key… 
2018
2018
PTB/nPTB: master regulators of neuronal fate in mammals
PTB was initially discovered as a polypyrimidine tract-binding protein (hence the name), which corresponds to a specific RNA… 
Highly Cited
2018
Highly Cited
2018
LncRNA Meg3 protects endothelial function by regulating the DNA damage response
Abstract The role of long non-coding RNAs (lncRNAs) in regulating endothelial function through the DNA damage response (DDR… 
2017
2017
Inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells
Background:Human polypyrimidine tract binding protein 3 (PTBP3) was first discovered in 1999 and has been well characterised as a… 
2015
2015
Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation
Polypyrimidine tract binding protein (PTBP1) is a widely expressed RNA binding protein that acts as a regulator of alternative… 
2014
2014
The effects of PTBP3 silencing on the proliferation and differentiation of MKN45 human gastric cancer cells.
2012
2012
ROD1 Is a Seedless Target Gene of Hypoxia-Induced miR-210
Most metazoan microRNA (miRNA) target sites have perfect pairing to the “seed” sequence, a highly conserved region centering on… 
2012
2012
Expression analysis of the polypyrimidine tract binding protein (PTBP1) and its paralogs PTBP2 and PTBP3 during Xenopus tropicalis embryogenesis.
The PTB (polypyrimidine tract binding protein) family of RNA-binding proteins plays a critical role in development through the… 
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