PTBP3 gene

Known as: PTBP3, Polypyrimidine Tract Binding Protein 3 Gene, polypyrimidine tract binding protein 3 
This gene plays a role in RNA splicing, cellular differentiation and erythropoiesis.
National Institutes of Health

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4 relations
ErythropoiesisPolypyrimidine Tract-Binding Protein 3RNA BindingRNA Splicing

Papers overview

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2018
2018
PTBP3-Mediated Regulation of ZEB1 mRNA Stability Promotes Epithelial-Mesenchymal Transition in Breast Cancer.
The RNA polypyrimidine tract-binding protein PTBP3 is a little studied paralog of PTBP1, which has oncogenic properties. In this… (More)
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2018
2018
PTBP3 splicing factor promotes hepatocellular carcinoma by destroying the splicing balance of NEAT1 and pre-miR-612
Nuclear-enriched RNA-binding proteins (RBPs) are mainly involved in transcriptional regulation, which is a critical checkpoint to… (More)
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2018
2018
PTBP3 contributes to the metastasis of gastric cancer by mediating CAV1 alternative splicing
Polypyrimidine tract-binding protein 3 (PTBP3) is an essential RNA-binding protein with roles in RNA splicing, 3′ end processing… (More)
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2018
2018
The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes
Activation-induced cytidine deaminase (AID) mediates class switching by binding to a small fraction of single-stranded DNA (ssDNA… (More)
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2017
2017
Inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells
Background:Human polypyrimidine tract binding protein 3 (PTBP3) was first discovered in 1999 and has been well characterised as a… (More)
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2015
2015
Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation
Polypyrimidine tract binding protein (PTBP1) is a widely expressed RNA binding protein that acts as a regulator of alternative… (More)
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2014
2014
The effects of PTBP3 silencing on the proliferation and differentiation of MKN45 human gastric cancer cells.
AIMS PTBP3 overexpression inhibits the differentiation of leukemia cells; however, its effects on the differentiation and… (More)
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2014
2014
Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis.
Lung squamous cell carcinoma (SCC) is thought to arise from premalignant lesions in the airway epithelium; therefore, studying… (More)
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2012
2012
ROD1 Is a Seedless Target Gene of Hypoxia-Induced miR-210
Most metazoan microRNA (miRNA) target sites have perfect pairing to the "seed" sequence, a highly conserved region centering on… (More)
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2012
2012
Expression analysis of the polypyrimidine tract binding protein (PTBP1) and its paralogs PTBP2 and PTBP3 during Xenopus tropicalis embryogenesis.
The PTB (polypyrimidine tract binding protein) family of RNA-binding proteins plays a critical role in development through the… (More)
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