PSI 7977

Known as: 7977, PSI, PSI-7977, PSI7977 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2016
02420102016

Papers overview

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2016
2016
Hepatitis disease caused by hepatitis C virus (HCV) is a severe threat to global public health, affecting approximately 3% of the… (More)
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2016
2016
The 2016 Lasker-DeBakey Clinical Medical Research Award was given to three scientists working on different stages of the… (More)
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2013
2013
The current available treatment for hepatitis C virus (HCV)-the causative of liver cirrhosis and development of liver cancer-is a… (More)
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Highly Cited
2012
Highly Cited
2012
PSI-7977, a prodrug of 2'-F-2'-C-methyluridine monophosphate, is the purified diastereoisomer of PSI-7851 and is currently being… (More)
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2012
2012
The 2 '-deoxy-2 '-fluoro-2 '-C-methyluridine nucleotide prodrug, PSI-7851 and its single diastereomer PSI-7977 have displayed… (More)
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2012
2012
volume 30 number 11 november 2012 nature biotechnology IDX184, unlike BMS-986094, is not based on phosphoramidate chemistry. BMS… (More)
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2011
2011
PSI-352938, a cyclic phosphate nucleotide, and PSI-353661, a phosphoramidate nucleotide, are prodrugs of β-D-2'-deoxy-2'-α-fluoro… (More)
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2011
2011
The launch of first-generation protease inhibitors (PIs) was a major step forward in hepatitis C virus (HCV) treatment. However… (More)
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2011
2011
  • Nature Reviews Drug Discovery
  • 2011
hepatitis C virus (HCV) infection involves treatment with ribavirin and pegylated interferon (PEG-IFN). This stimulates the… (More)
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2010
2010
A phosphoramidate prodrug of 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate, PSI-7851, demonstrates potent anti… (More)
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