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PS1145

Known as: PS-1145 
National Institutes of Health

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2 relations

Broader (2)

Heterocyclic Compounds, 3-RingPyridines

Papers overview

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2016
2016
The effect of an IκB-kinase-β(IKKβ) inhibitor on tobacco smoke-induced pulmonary inflammation
ABSTRACT Purpose of the Study: Inactivation of NF-κB with IKKβ knockout mice reduces tobacco smoke-induced pulmonary inflammation… 
2016
2016
Central Leptin and Tumor Necrosis Factor-α (TNFα) in Diurnal Control of Blood Pressure and Hypertension*
Leptin and TNFα can individually work in the brain to affect blood pressure; however, it remains unknown whether these two… 
2015
2015
Administration of IκB‐kinase inhibitor PS1145 enhances apoptosis in DMBA‐induced tumor in male Wistar rats
Nuclear factor kappa‐B (NF‐κB), a key anti‐apoptotic factor, plays a critical role in tumor cell growth, metastasis, and… 
2014
2014
Spatial control of bone formation using a porous polymer scaffold co-delivering anabolic rhBMP-2 and anti-resorptive agents.
Current clinical delivery of recombinant human bone morphogenetic proteins (rhBMPs) utilises freeze-dried collagen. Despite… 
2013
2013
Paraptosis and NF-κB activation are associated with protopanaxadiol-induced cancer chemoprevention
BackgroundProtopanaxadiol (PPD) is a triterpenoid that can be prepared from steamed ginseng. PPD possesses anticancer potential… 
2013
2013
Role of PKC-α in NF-κB-MT1-MMP-mediated activation of proMMP-2 by TNF-α in pulmonary artery smooth muscle cells.
We sought to evaluate the mechanism(s) associated with pro matrix metalloprotease 2 (proMMP-2) activation in bovine pulmonary… 
2008
2008
Teasing out monocyte trafficking mechanisms.
In this issue of Blood , Xu and colleagues demonstrate that mechanisms controlling monocyte recirculation through peripheral and… 
2004
2004
Selective efficacy of depsipeptide in a xenograft model of Epstein-Barr virus-positive lymphoproliferative disorder.
BACKGROUND Immune-compromised individuals are at increased risk for developing aggressive Epstein-Barr virus (EBV)-associated… 
Highly Cited
2003
Highly Cited
2003
Moving disease biology from the lab to the clinic
Multiple myeloma (MM) cells home to and adhere to extracellular matrix proteins and to bone marrow stromal cells (BMSCs); and in… 
Highly Cited
2003
Highly Cited
2003
Biologic sequelae of c-Jun NH2-terminal kinase (JNK) activation in multiple myeloma cell lines
Although c-Jun NH2-terminal kinase (JNK) is activated by treatment with therapeutic agents, the biologic sequelae of inhibiting… 
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